First described in 1964 by Gaoni and Mechoulam, the CBG or cannabigerol is one of the cananbinoids exclusively produced by cannabis plants in the glandular heads of their trichomes. While the CBG content of most plants is low or very low – in most cases less than 1% – the importance of this compound is crucial for the synthesis of other cannabinoids, as it has been known for 4 decades (Shoyama , Yagi and Nishioka in the journal Phytochemistry, October 1975). Normally, hemp varieties contain higher percentages of CBG than those of narcotic cannabis.


CBG is a non-psychoactive phytocannabinoid, that is, it is naturally synthesized by plants and does not cause a feeling of drunkenness when consumed. It is attributed multiple medicinal properties that can be used in a wide range of medical conditions, and it is also (its acid form, to be more exact) the precursor of the main cannabinoids secreted in the trichomes, such as THCA or CBDA, which explains the low content in this compound compared to those that originate from it.

It is important to keep in mind that most of the evidence comes from preclinical studies, which means that the safety and efficacy of CBG have not yet been tested in humans. That said, CBG studies have revealed a wide range of possible benefits.


Stimulates bone formation and healing: The effects of CBG and other cannabinoids on bone marrow cultures were investigated. The results showed that they could stimulate bone marrow stem cells indirectly through the CB2 receptor. This suggests that CBG and other cannabinoids can help the healing of bone fractures by promoting the growth and formation of new bone.

Tumor growth decreases: It was reported that CBD, CBG and CBC along with other cannabinoids slowed the progression and growth of several tumors and cancer cells. By slowing tumor growth, these cannabinoids could extend the lives of people fighting cancer.

Antifungal and antibacterial treatment: The antifungal and antimicrobial properties of various cannabinoids, including CBG, are currently under investigation. CBG proved to be highly effective against MRSA (methicillin-resistant Staphylococcus aureus) in a 2008 study. SARM is a strain of bacteria highly resistant to antibiotics.

Relieves pain: CBG and other cannabinoids are known to have analgesic effects in various conditions, including pain caused by multiple sclerosis and cancer. According to a 2008 article, clinical trials have shown that synthetic cannabinoids are well tolerated and effective, and can have an additional analgesic effect when combined with other pharmaceutical products for pain treatment.

Reduces inflammation: Cannabinoids such as CBG have the ability to reduce inflammation by targeting specific molecules responsible for inflammation in various disease states, including symptoms of pain, cancer and even inflammatory bowel disease. For example, studies show that CBG can act as a COX-2 inhibitor, similar to widely used medications called nonsteroidal anti-inflammatory drugs (NSAIDs).

Treatment of overactive bladder: Cannabis and cannabinoid preparations have been used to treat various bladder dysfunctions. In a 2015 study, researchers tested the effects of CBG and other cannabinoids on experimentally induced bladder contractions. It was found that CBG and THCV had the strongest capacity to reduce bladder contractions.

Psoriasis and skin treatment: CBG and other cannabinoids may be useful for treating various skin disorders, due to the presence of cannabinoid receptors in the skin. In a 2007 study, CBG was shown to inhibit keratinocyte proliferation, which suggests a role for CBG in the treatment of psoriasis.

Glaucoma treatment: In a 1990 study, treatment with THC and CBG increased aqueous flow two to three times in animal models of glaucoma. Increased water flow can help reduce intraocular pressure in cases of glaucoma.

Depression and anxiety treatment: It is well known that THC can help patients suffering from depression and anxiety. It has been found that CBG has similar effects, but without causing the psychopropic effect that THC is known for. A 2016 report suggests that non-psychoactive cannabinoids such as CBG could be a possible alternative to treat anxiety and depression.


Neuroprotective effects: In a 2015 study on animal models of Huntington’s disease, it was discovered that CBG is “extremely active as a neuroprotective.” CBG treatment improved movement and recovery in mice with Huntington and neurons protected against degeneration. The CBG also showed possible anti-inflammatory and antioxidant effects. The researchers concluded that CBG should be studied further as a treatment for neurodegenerative disorders.


CBG is the basic component for many Marijuana compounds, including THC and CBD. Cannabinoids are the active chemicals found in Cannabis. They are plant specific and are known to affect the human body in many ways. While you may have heard of cannabinoids such as THC and CBD, not many realize how important CBG is when it comes to Marijuana.

CBG is not psychoactive and can be considered as the “stem cell” or “progenitor” of other cannabinoids.

After being synthesized, CBG quickly converts to other cannabinoids through natural processes that occur within the Cannabis plant. This explains the low CBG content of most Marijuana varieties.

More CBG has been found in hemp than in cannabis, so it is thought that this variety has a recessive gene that stops the production of synthases, the enzymes responsible for CBGA breaking down and evolving into another cannabinoid. This discovery about the absence of synthases in hemp means that new hybrids can be made to create genetics that are richer in this cannabinoid. There are already some seed banks that offer strains with a higher proportion of CBG, the result of hybridization of different varieties.

Commercial interest:

As research on CBG progresses, this is undoubtedly making its way to the top positions of curative cannabinoids due to the enormous potential it shows in studies, hence the market for varieties with higher concentrations of this CBG molecule whether they are of great commercial interest and be the new trend in the cannabis market.
A high demand for THC-free and high-CBG products is expected. Currently, only a limited number of companies offer high quality CBG seeds and that creates a huge opportunity.
A seed of a variety of hemp free of psychoactive components with high CBG, makes it unique in the market, with highly medicinal properties and far from any bureaucratic and / or legal obstacles. At the same time, it allows the possibility of opening up to any possibility of products such as oils, biomass, flowers, edibles, extracts, topics, drinks, concentrates, tinctures. In extractions, the CBG requires less purification than, therefore, the costs are lower. It has a strong economic performance, producing surprisingly productive crops, allowing a better evaluation of its medicinal properties, under optimal cultivation conditions. Finally, revenues are much higher than in the case of CBD.



In this new world where all and every day is putting on test so fast, we have to consider the facts than less invasive to the body and system the best results will be achieved, CBG is one of the most primary forms of cannabidiols, this make the resonance of the most natural source where the cannabinoid system can connect easily, there is a lot to discover, evidence is showing at every minute, day after day CBG isa proving solution for health obstacles, less invasive, far way from over dosis, is getting very popular in the understanding of what will be the best product to keep and not be ignored. The particular amount of CBG than you can take out of the plant is around 1%, so is not very large the amount. In any case the oils we are going to study in the deep it will be CBG, this external cannabidiols are making a great effect, is important to understand that to get the real stuff you must consider to read the labels and to make a research over the brand you are about to purchase, one of the important stuff will be if there is a 3rd lab tested, another important is to know if the product itself is organic, the package, the price. Is also very interesting if you find the flower of the CBG string, the review I have found are very positive regarding the effect, the look, smell, and the after smoke feeling, some of them says it feels like a great deal of calmness and relax, NOT hight or stone, but with a very particular relaxing stage. In many countries still not legal to use any of the cannabidiols, we are getting close in to an end of regulations, I am afraid than the big players haven’t start to have presence in the cannabidiols market as they shut, and probably when they arrive will be a lot of regulation and vanish the small brands, or the ones who are not available to sustain a good product in the whole concept of what is coming, I must say, than in another hand is good, because is a lot of crap and bad business only printing money and not carrying for the end consumer. I will came with a project of CBG in a very narrow way to help myself with inflammation and stress, thanks for your time ad I wish you a great weekend and life, big love to you all.


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Fitzcharles MA, Ste-Marie PA, Hauser W, Clauw DJ, Jamal S, Karsh J, Landry T, LeClercq S, McDougall JJ, Shir Y, Shojania K, Walsh Z. Efficacy, tolerability, and safety of cannabinoid treatments Care and Research. 2016.



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