Cannabis in obstetrics and gynecology

Women consume cannabis for therapeutic purposes since ancient times. Today, science indicates that THC and CBD could be safe alternatives to treat many gynecological conditions. Read on to find out about current research and how cannabis derivatives can help women throughout their lives.

The use of medical cannabis and women’s health have been related since the man knows the herb. The use of cannabis in ancient obstetrics and gynecology seems to reveal a connection between the nature of women and the uniqueness of the female flower of cannabis. Throughout history, cannabinoids have acted as great allies in various diseases related to our complex reproductive system. And today, the growing cannabis market offers oils, bath products, capsules, topical creams and even buffers with THC, CBD or a combination of both cannabinoids.


Archaeologists discovered references to the use of medical cannabis for women’s health in texts from ancient Mesopotamia from around 2000 B.C. At this time, the herb was mixed with other plant substances to treat menstrual pain, and since then, women around the world have consumed weed for many reasons. This fragrant plant was included even in the Egyptian pharmacopeia, where it is mentioned many times in the medical texts of ancient Persia, and was consumed by women from all over the Mediterranean and Europe. The same happened in India and in the Chinese Empire, as indicated in a detailed historical analysis conducted by Ethan Russo.

The herb used to be administered through methods quite similar to those currently used: orally, rectally, vaginally, topically and by fumigation (when inhaling the smoke from the burning of cannabis flowers). We can find clear descriptions of these methods in ancient medical texts, with specific references to gynecological symptoms and diseases to be treated. Among these conditions are painful cramps, bleeding, infections, swelling, menstrual disorders or menopausal symptoms. Cannabis also helped relieve contractions and facilitate the process of childbirth, but it was also used to cause abortion. This is a particularly enigmatic aspect.


During the 19th century, cannabis derivatives were included in official pharmacopoeias to treat a wide range of diseases, and their use in gynecology was recommended by the leading eminences of medicine, as well as Queen Victoria. This intelligent queen was also the Empress of India, where many herbs and natural remedies came from. Centuries after his death, she became famous in the cannabis community worldwide, as it was discovered that she used cannabis tincture to relieve his menstrual cramps.

Irish physician William Brooke O’Shaughnessy continued Queen Victoria’s line by validating traditional cannabis use in India, discovering new applications and recommending cannabis extracts for a wide variety of therapeutic purposes. O’Shaughnessy noted the effectiveness of cannabis in reducing uterine bleeding, and in the mid-1900s, doctors promoted cannabis tinctures for menstrual conditions and other diseases of women. A new branch of clinical research on cannabis was being initiated where women’s health was included, but then the ban came and everything changed.


After the dark era of the ban, which today is not much brighter, the science behind centuries of anecdotal data was beginning to be confirmed thanks to a great deal of new research.

Endocannabinoid system

(ECS) It is a very important regulatory network with functions related to mood, metabolism, appetite, immune system response, memory and pain perception. Ultimately, one of the main tasks of the SEC is to help the body maintain a state of internal balance known as homeostasis.

The ECS plays a role in female hormonal balance and in reproductive processes. Cannabinoids derived from cannabis are capable of interacting with the cannabinoid receptors of our body, and this is where “magic” arises.


Today, we have strong evidence on the properties of cannabis to relieve pain, both in clinical studies and in patient experience. The research also confirms the anti-inflammatory effects of cannabis derivatives, which can help reduce pain. Today, more and more women consume cannabis in various ways to treat Painful symptoms such as uterine inflammation and other problems related to menstruation.

Despite that, there is no rigorous study that has investigated the properties of cannabis against nausea during a woman’s menstruation. That said, THC is famous for its antiemetic properties, and the compound has been involved in the treatment of chemotherapy for years. Research on the specific effects of cannabis on menstruation pain is also lacking, but it has been found that the interaction between THC and estrogen provides greater pain relief. This result leads to the conclusion that cannabis could be more effective in relieving pain in women than in men.


There is very little research available on the effects of cannabis on premenstrual syndrome, despite the known benefits for pain, muscle tension, headache and mood. Women who live in areas where cannabis is completely legal are more likely to try products that contain THC and CBD when it comes to relieving premenstrual syndrome symptoms related to mood. In most of the world, CBD products can be consumed as a home treatment for the conditions mentioned above, including anxiety and mood disorders caused by premenstrual syndrome.


Endometriosis is a fairly common and painful health problem that causes the internal tissue of the uterus to grow elsewhere, generating severe pelvic pain, scarring and risk of infertility. Endometriosis affects approximately 1 in 10 women worldwide during their fertile years.

A recent online survey showed that Australian women with endometriosis who consumed cannabis flowers or extracts, CBD oil, applied heat and made changes to their diet, were the most successful in terms of pain reduction. Physical interventions such as yoga, stretching and exercise were rated as less effective. Despite these findings, the most common remedy for endometriosis pain control is still anti-inflammatory medications, although they have considerable side effects.


One study showed that 68.5% of women who used marijuana before sex had a more pleasant experience. In most cases, women who consume small amounts of cannabis experience an increase in sexual desire, while higher doses of THC have a negative effect. The positive effect of cannabis on anxiety can also be reflected in sexual life, and also has the capacity to increase physical sensitivity. Although cannabis use during sex has always been popular, research has not provided clear evidence of how sexual experience improves. And it is not an easy task.

However, new health care companies involved in the legal cannabis business have been developing products with cannabinoids aimed at improving sexual life. These products contain THC, CBD, or a combination of both, and come in the form of lubricants, creams, soothing oils, suppositories and, of course, a large number of sweet aphrodisiac edibles. Consumer opinions are largely positive, particularly with regard to pain reduction during or after sex.


Medicine prior to industrialization considered that “Indian hemp” had a great capacity to increase uterine contractions during childbirth, while also being beneficial against bleeding. There may still be a lot left for us to see edibles or vaporizers in the delivery room, but it is something worth to explore.

The Washington University School of Medicine in Seattle has initiated a study recently called “The Moms + Marijuana Study. For the first time, researchers are trying to assess whether cannabis use to relieve prenatal nausea is safe for baby’s development. The results, which will include images of the brain of the developing fetus, could change the way cannabis is perceived in the medical community.

Women who go through menopause experience several symptoms, many of which are difficult to treat directly. More and more clinical and anecdotal evidence suggests that cannabis, and in particular CBD, has the potential to relieve some symptoms of menopause. Research has shown that the endocannabinoid system regulates, among other things, mood, sleep and pain perception. There is also scientific evidence on the complex role of the endocannabinoid system (ECS) in female fertility, and researchers establish a clear relationship between estrogen hormones, endocannabinoid anandamide and ECS functions.

In addition, laboratory research argues that cannabinoids may help regulate bone development, reducing the common risk of postmenopausal osteoporosis. Research indicates that CBD can bind to bone cell receptors, which inhibits the deterioration process and slows the loss of bone density. Despite the lack of conclusive evidence, cannabis use even during menopause can help the endocannabinoid system maintain homeostasis.

Although an adequate combination of THC and CBD could be more effective for menopause problems, it has been shown that CBD is effective on its own in treating sleep problems and menopausal mood, without exerting intoxicating effects. THC.


Unfortunately, studies show that women develop a tolerance to cannabis faster than men and suffer more adverse effects from possible withdrawal symptoms. It also seems that cannabis use affects more women than men in the region of the brain that controls “spatial memory. But on top of that, like any other substance, cannabis has mild side effects and may not work for everyone.

Although most people can safely test CBD, greater caution should be taken with the intoxicating cannabinoid, THC. In legal markets, seeds or products containing a ratio of 1: 1 of CBD: THC, or only CBD with almost no THC can be obtained. Those who want to consume THC can also try microdosing, that is, take small doses of THC throughout the day, without getting “placed.” This should also provide benefits such as relief from inflammation and pain, but without significantly affecting the mind. On the other hand, those who are very familiar with THC can choose from a large number of strains.

Finally, a survey of US women. Published in Obstetrics and Gynecology in June 2019 demonstrates cannabis use among women, backed by a large amount of anecdotal data. Of the 1,011 women with an average age of 37 years, 36% reported that they consumed it to treat a specific condition, such as pain, depression or anxiety. Of these women, 16% said they used cannabis to treat a gynecological discomfort such as menstrual cramps. In addition, most of the women surveyed considered cannabis use to treat a gynecological condition.


Russo, Ethan. (2002). Cannabis treatments in obstetrics and gynecology: a historical review. Journal of Cannabis Therapy.

Women and cannabis: medicine, science and sociology – Cannabis Therapeutics Magazine, Dr. Ethan Russo

Brents LK. Marijuana, the Endocannabinoid System and the Female Reproductive System. Yale J Biol Med. 2016;89(2):175–191. Published 2016 Jun 27

Women and cannabis: medicine, science, and sociology – NLM Catalog – NCBI

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects

Effects of Medical Marijuana on Migraine Headache Frequency in an Adult Population. – PubMed – NCBI

Studies on CBD and Anxiety

Studies on CBD and Depression

Cannabidiol as a Potential Treatment for Anxiety Disorders | SpringerLink


This publication was written with only one purpose to inform and send our dear visitors one more opinion about the fascinating world of the Canabidiols and their possible alternatives, we must take into account that the information published here is mixed, both from external sources, as well of own authorship for some notes and general points of view.