CBD OIL AND ASTHMA

CBD OIL AND ASTHMA

Asthma is a disease of the respiratory tract, which currently affects a high percentage of the world’s population. It is usually detected in many cases since childhood when children have wheezing when they breathe or have had a respiratory infection such as bronchitis or pneumonia.

It is common to see that most people who suffer from asthma, whether from small or already in adulthood, also have allergies. This disease is chronic and has no cure, but it can be treated with a number of special drugs and, more recently, with cannabis. Among the many properties that this plant has, there are a number of advantages that can control asthma symptoms.

Although research is still lacking in this regard, cannabis has given very good results in the treatment of this pathology, mainly due to the action of its best-known cannabinoids such as THC, THCV, CBG and CBD. The latter promises to be the uncoated hero of many diseases, but now let’s see in this article how he can treat this respiratory condition.

Why use CBD to fight asthma?

To begin, it should be clarified that cannabidiol or CBD is only one of the more than 400 phytocannabinoids present in the cannabis Sativa plant, popularly known as marijuana. This compound is highly effective in the treatment of different diseases and disorders, thanks to its multiple therapeutic and medicinal properties.

Well but if CBD is part of cannabis, can it drug me? CBD is not psychoactive, so don’t worry about having a high if you consume it. The narcotic effect is mainly caused by another phytocannabinoid, THC or tetrahydrocannabinol. Do not worry: there are currently ways to consume CBD without THC, so you can only keep the therapeutic effects.

Among the benefits of CBD, one of the most prominent is it is anti-inflammatory and analgesic power, so it helps mitigate the pain and swelling that is caused by different factors. As these are some of the characteristics of diseases such as asthma, among many others, research has begun with CBD therapies to minimize the discomfort caused by asthma in the respiratory tract, obtaining very good results.


WHAT IS ASTHMA?

If you have ever felt asphyxiation or that the air you breathe is not enough, you know that it is an almost panic situation. Asthma is like that, a chronic respiratory disease that makes it hard for the person to have a good breath. It occurs when the airways become inflamed and narrow, complicating the passage of oxygen to the lungs.

Under normal conditions, by relaxing the diaphragm, the lungs can expand and receive more air. During an asthma crisis, the bronchial tract becomes irritated and inflamed, which can cause the diaphragm to contract, complicating breathing and generating an involuntary hiss when breathing.

The causes of asthma are varied: it can occur due to emotional, environmental factors such as dust, smoke and cold, or also genetic. This disease can be lethal and does not have a specific cure, but with good treatment, the risk decreases greatly. Thanks to its anti-inflammatory properties, CBD is thought to be a natural alternative to treat asthma.

Asthma and its effects on the human body

We already know that asthma is a disease of the respiratory tract. But what does it do in the body? Well, basically, when there is a crisis or asthma attack, the lungs are temporarily reduced, making breathing difficult and even painful. This disease has a strong hereditary component, but it can also be caused by allergenic effects such as dust, certain odours, climatic and even emotional factors.

The first thing that happens when someone suffers from asthma, is the inflammation and from it all the other symptoms are released. This condition is continuous because even when the person feels that he is breathing well and does not have an asthma attack, the airways remain inflamed.

Inflammation also generates hyperreactivity, that is, the high sensitivity of the respiratory passages. That is why when someone is asthmatic, in a state of normalcy, the simple fact of receiving cold air, smelling perfume or a little smoke may cause a great asthmatic reaction. In short: it is unpredictable. Another effect of inflammation is bronchoconstriction, an excessive contraction and usually full of the mucosa, in the respiratory tract.


CBD FOR ASTHMA

The various medicinal properties that CBD has have earned this cannabinoid a growing reputation. In the case of asthmatic people, CBD can help as:

Anti-inflammatory

CBD has anti-inflammatory properties. This is stated because the CBD interacts directly with the receptors of the endocannabinoid system of our body, managing to reduce the levels of inflammation of the tissues. In asthma, tissue inflammations are constant, so CBD can help.

Antispasmodic

Because of its calming effect, CBD is very effective in relieving muscle spasms or bronchospasms that can affect a person during an asthma crisis. For many patients, these spasms are the most desperate situation, so the CBD could fight them.

Expectorant

Although there is still insufficient solid evidence, many cannabis users around the world have indicated that after vaporizing or smoking, they have felt an expectorant effect. This, again, would allow decongesting the airways.

Antibiotic

According to research, asthma can have genetic causes or it can develop due to bacterial infections during childhood, affecting the immune system. Since CBD and CBG cannabinoids have been shown to have broad-spectrum bactericidal effects, they can help with asthma antimicrobial treatment.

Analgesic

However, many patients indicate that their chest hurts when they are in the middle of an asthma crisis. CBD has analgesic effects, so it can relieve the pressure of the lungs and diaphragm, as well as lessen the pain associated with asthma. However, in this case, its use would only correspond to crises.

Contradictory as it may seem, experiences have shown that one of the most recommended options for this treatment is to inhale or vaporize CBD. Why? Because in this way you provide your body with a maximum CBD content that will help you fight asthma attacks more quickly.

You can get CBD oil with different concentrations. You should only talk to your doctor before consuming this product to treat asthma or self-medicate. However, vaporizing this oil has no major negative effects on the lungs or throat. However, if there is any discomfort or the symptoms get worse, it is better to opt for an edible form of CBD.

The main difference between vaporizing CBD and consuming it in another way is that the first option acts more efficiently when an asthmatic crisis occurs. This is because when you vaporize, you take advantage of the CBD at its maximum concentration and send it directly through the airways. Otherwise, you would have to wait for a little before perceiving the therapeutic effects.


The dose of CBD for Asthma

Each person is different and so is their response to CBD. That is why the doses can vary between one individual and another, also depending on the concentration of CBD you are using. Normally, it begins with a low dose, depending on the case of asthma, and if no results are observed, it can be increased if the doctor authorizes it.

As previously mentioned, the best way to consume CBD in cases of asthma is to vaporize its oil, but if for some reason you do not want or can not consume it like this, you can apply it sublingually. You should only apply a couple of drops under the tongue and keep them until they are completely absorbed.

Vaporizing CBD oil, consuming it in the form of capsules or dissolving the drops with a meal, are the easiest ways to control the dosage. Be careful because, although there is no record of any death or serious side effect from CBD consumption, a very high dose can cause certain discomforts such as drowsiness, diarrhoea or vomiting, and even more so if it is the first time you have the tests.

Personal experience

Since I have a memory I was going into the emergency of the hospital from my home town with a very deep Asthma attack, getting an adrenaline shot in my leg, and right after a long blackout, waking up later with my mom or dad in the side taking care of me. While I was growing up the development of my Asthma crisis where continuously, later on with oxygen and salbutamol, once we move to an island in the Caribbean, and that was even worse, I was in the hospital for a week.

Endless treatments and test’s, physical and medical, no one has cured me once for all, I have a very allergic and reactive Asthma type, today I can say is a very annoying problem, some limitations can make my life hard when I can’t get the medicine.

One of the best results where achieved when I decide to make a very strict diet, no sugar, fats, strong or spice food elements, also dedicate my self to training more, swimming, cardio, and mountain bike, the change was impressive, and the efficiency really great, no Asthma for long time, and better style with my normal life.

Researching and practising with different therapies I discover CBD oil, and have noticed when I take it I was available to breathe much better, sleep dipper and have more time between crisis, recently I m drinking 10% RAW ENDOCA CBD OIL soft gel, and 3% RAW ENDOCA CBD OIL drops, I’m very pleased to say than the long term of treatment can give me the perfect results for leaving behind allergies and Asthma attacks, I don’t think it will be only the CBD than will help, but a fundamental ingredient to always have.

How I meet CBD for the first time?

I was travelling to another continent a long trip so, jetlag for a while, 2-3 days after I have arrived went to my friends house for lunch and we talk about it, he told me, I may have the solution for it, “here you go”, and that was a dark brown little bottle with some type of liquid in it, right away I ask him, what is this about, what is in the bottle? “This is a CBD oil 50%, It will help you to get over the effects of the jetlag, take 2 drops and then wait” So I took right away the drops,  after some time I went back home, relax a bit and fall sleep, next day felt fresh, much better and no symptoms of jetlag, ready to roll, so that was my first experience with CBD, and I will go later in this subject about the jetlag and CBD.

Now more committed to keeping discovering their effects on myself making a personal journey about it, and sharing it with you with big pleasure.

References

– Leinow,, L. and Birnbaum, J. (2017). CBD: A Patient’s Guide to Medicinal Cannabis. North Atlantic Books.

– Vuolo, F., Abreu, S., Michels, M., Xisto, D., Blanco, N., Hallak, J., Zuardi, A., Crippa, J., Reis, C., Bahl, M., Pizzichinni, E., Maurici, R., Pizzichinni, M., Rocco, P. and Dal-Pizzol, F. (2019). Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma. European Journal of Pharmacology, 843, pp.251-259.

– Pini, A., Mannaioni, G., Pellegrini-Giampietro, D., Beatrice Passani, M., Mastroianni, R., Bani, D. and Masini, E. (2012). The Role of Cannabinoids in Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke. Current Drug Targets, 13(7), pp.984-993.

– Who.int. (2019). WHO | Asthma. [En línea] Disponible en: https://www.who.int/respiratory/asthma/en/ . 

– WebMD. (2019). Guide to Asthma. [En línea] Disponible en: https://www.webmd.com/asthma/what-is-asthma#1

THE CBG OIL

THE CBG OIL

First described in 1964 by Gaoni and Mechoulam, the CBG or cannabigerol is one of the cananbinoids exclusively produced by cannabis plants in the glandular heads of their trichomes. While the CBG content of most plants is low or very low – in most cases less than 1% – the importance of this compound is crucial for the synthesis of other cannabinoids, as it has been known for 4 decades (Shoyama , Yagi and Nishioka in the journal Phytochemistry, October 1975). Normally, hemp varieties contain higher percentages of CBG than those of narcotic cannabis.


IS CBG A PSYCHOACTIVE CANNABIDIOL?

CBG is a non-psychoactive phytocannabinoid, that is, it is naturally synthesized by plants and does not cause a feeling of drunkenness when consumed. It is attributed multiple medicinal properties that can be used in a wide range of medical conditions, and it is also (its acid form, to be more exact) the precursor of the main cannabinoids secreted in the trichomes, such as THCA or CBDA, which explains the low content in this compound compared to those that originate from it.

It is important to keep in mind that most of the evidence comes from preclinical studies, which means that the safety and efficacy of CBG have not yet been tested in humans. That said, CBG studies have revealed a wide range of possible benefits.


THE GREAT BEFEFITS OF CBG

Stimulates bone formation and healing: The effects of CBG and other cannabinoids on bone marrow cultures were investigated. The results showed that they could stimulate bone marrow stem cells indirectly through the CB2 receptor. This suggests that CBG and other cannabinoids can help the healing of bone fractures by promoting the growth and formation of new bone.

Tumor growth decreases: It was reported that CBD, CBG and CBC along with other cannabinoids slowed the progression and growth of several tumors and cancer cells. By slowing tumor growth, these cannabinoids could extend the lives of people fighting cancer.

Antifungal and antibacterial treatment: The antifungal and antimicrobial properties of various cannabinoids, including CBG, are currently under investigation. CBG proved to be highly effective against MRSA (methicillin-resistant Staphylococcus aureus) in a 2008 study. SARM is a strain of bacteria highly resistant to antibiotics.

Relieves pain: CBG and other cannabinoids are known to have analgesic effects in various conditions, including pain caused by multiple sclerosis and cancer. According to a 2008 article, clinical trials have shown that synthetic cannabinoids are well tolerated and effective, and can have an additional analgesic effect when combined with other pharmaceutical products for pain treatment.

Reduces inflammation: Cannabinoids such as CBG have the ability to reduce inflammation by targeting specific molecules responsible for inflammation in various disease states, including symptoms of pain, cancer and even inflammatory bowel disease. For example, studies show that CBG can act as a COX-2 inhibitor, similar to widely used medications called nonsteroidal anti-inflammatory drugs (NSAIDs).

Treatment of overactive bladder: Cannabis and cannabinoid preparations have been used to treat various bladder dysfunctions. In a 2015 study, researchers tested the effects of CBG and other cannabinoids on experimentally induced bladder contractions. It was found that CBG and THCV had the strongest capacity to reduce bladder contractions.

Psoriasis and skin treatment: CBG and other cannabinoids may be useful for treating various skin disorders, due to the presence of cannabinoid receptors in the skin. In a 2007 study, CBG was shown to inhibit keratinocyte proliferation, which suggests a role for CBG in the treatment of psoriasis.

Glaucoma treatment: In a 1990 study, treatment with THC and CBG increased aqueous flow two to three times in animal models of glaucoma. Increased water flow can help reduce intraocular pressure in cases of glaucoma.

Depression and anxiety treatment: It is well known that THC can help patients suffering from depression and anxiety. It has been found that CBG has similar effects, but without causing the psychopropic effect that THC is known for. A 2016 report suggests that non-psychoactive cannabinoids such as CBG could be a possible alternative to treat anxiety and depression.

 

Neuroprotective effects: In a 2015 study on animal models of Huntington’s disease, it was discovered that CBG is “extremely active as a neuroprotective.” CBG treatment improved movement and recovery in mice with Huntington and neurons protected against degeneration. The CBG also showed possible anti-inflammatory and antioxidant effects. The researchers concluded that CBG should be studied further as a treatment for neurodegenerative disorders.


CBG IN ANOTHER WORDS AND CANNABIDIOL WORLD

CBG is the basic component for many Marijuana compounds, including THC and CBD. Cannabinoids are the active chemicals found in Cannabis. They are plant specific and are known to affect the human body in many ways. While you may have heard of cannabinoids such as THC and CBD, not many realize how important CBG is when it comes to Marijuana.

CBG is not psychoactive and can be considered as the “stem cell” or “progenitor” of other cannabinoids.

After being synthesized, CBG quickly converts to other cannabinoids through natural processes that occur within the Cannabis plant. This explains the low CBG content of most Marijuana varieties.

More CBG has been found in hemp than in cannabis, so it is thought that this variety has a recessive gene that stops the production of synthases, the enzymes responsible for CBGA breaking down and evolving into another cannabinoid. This discovery about the absence of synthases in hemp means that new hybrids can be made to create genetics that are richer in this cannabinoid. There are already some seed banks that offer strains with a higher proportion of CBG, the result of hybridization of different varieties.


Commercial interest:

As research on CBG progresses, this is undoubtedly making its way to the top positions of curative cannabinoids due to the enormous potential it shows in studies, hence the market for varieties with higher concentrations of this CBG molecule whether they are of great commercial interest and be the new trend in the cannabis market.
A high demand for THC-free and high-CBG products is expected. Currently, only a limited number of companies offer high quality CBG seeds and that creates a huge opportunity.
A seed of a variety of hemp free of psychoactive components with high CBG, makes it unique in the market, with highly medicinal properties and far from any bureaucratic and / or legal obstacles. At the same time, it allows the possibility of opening up to any possibility of products such as oils, biomass, flowers, edibles, extracts, topics, drinks, concentrates, tinctures. In extractions, the CBG requires less purification than, therefore, the costs are lower. It has a strong economic performance, producing surprisingly productive crops, allowing a better evaluation of its medicinal properties, under optimal cultivation conditions. Finally, revenues are much higher than in the case of CBD.


 

Coclusion:

In this new world where all and every day is putting on test so fast, we have to consider the facts than less invasive to the body and system the best results will be achieved, CBG is one of the most primary forms of cannabidiols, this make the resonance of the most natural source where the cannabinoid system can connect easily, there is a lot to discover, evidence is showing at every minute, day after day CBG isa proving solution for health obstacles, less invasive, far way from over dosis, is getting very popular in the understanding of what will be the best product to keep and not be ignored. The particular amount of CBG than you can take out of the plant is around 1%, so is not very large the amount. In any case the oils we are going to study in the deep it will be CBG, this external cannabidiols are making a great effect, is important to understand that to get the real stuff you must consider to read the labels and to make a research over the brand you are about to purchase, one of the important stuff will be if there is a 3rd lab tested, another important is to know if the product itself is organic, the package, the price. Is also very interesting if you find the flower of the CBG string, the review I have found are very positive regarding the effect, the look, smell, and the after smoke feeling, some of them says it feels like a great deal of calmness and relax, NOT hight or stone, but with a very particular relaxing stage. In many countries still not legal to use any of the cannabidiols, we are getting close in to an end of regulations, I am afraid than the big players haven’t start to have presence in the cannabidiols market as they shut, and probably when they arrive will be a lot of regulation and vanish the small brands, or the ones who are not available to sustain a good product in the whole concept of what is coming, I must say, than in another hand is good, because is a lot of crap and bad business only printing money and not carrying for the end consumer. I will came with a project of CBG in a very narrow way to help myself with inflammation and stress, thanks for your time ad I wish you a great weekend and life, big love to you all.


REFERENCES

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Weeding Out the Truth: Adolescents and Cannabis.Ammerman S, Tau G.J Addict Med. 2016 Mar-Apr; 10(2)

 

Fitzcharles MA, Ste-Marie PA, Hauser W, Clauw DJ, Jamal S, Karsh J, Landry T, LeClercq S, McDougall JJ, Shir Y, Shojania K, Walsh Z. Efficacy, tolerability, and safety of cannabinoid treatments Care and Research. 2016.