CBD OIL AND ASTHMA

CBD OIL AND ASTHMA

Asthma is a disease of the respiratory tract, which currently affects a high percentage of the world’s population. It is usually detected in many cases since childhood when children have wheezing when they breathe or have had a respiratory infection such as bronchitis or pneumonia.

It is common to see that most people who suffer from asthma, whether from small or already in adulthood, also have allergies. This disease is chronic and has no cure, but it can be treated with a number of special drugs and, more recently, with cannabis. Among the many properties that this plant has, there are a number of advantages that can control asthma symptoms.

Although research is still lacking in this regard, cannabis has given very good results in the treatment of this pathology, mainly due to the action of its best-known cannabinoids such as THC, THCV, CBG and CBD. The latter promises to be the uncoated hero of many diseases, but now let’s see in this article how he can treat this respiratory condition.

Why use CBD to fight asthma?

To begin, it should be clarified that cannabidiol or CBD is only one of the more than 400 phytocannabinoids present in the cannabis Sativa plant, popularly known as marijuana. This compound is highly effective in the treatment of different diseases and disorders, thanks to its multiple therapeutic and medicinal properties.

Well but if CBD is part of cannabis, can it drug me? CBD is not psychoactive, so don’t worry about having a high if you consume it. The narcotic effect is mainly caused by another phytocannabinoid, THC or tetrahydrocannabinol. Do not worry: there are currently ways to consume CBD without THC, so you can only keep the therapeutic effects.

Among the benefits of CBD, one of the most prominent is it is anti-inflammatory and analgesic power, so it helps mitigate the pain and swelling that is caused by different factors. As these are some of the characteristics of diseases such as asthma, among many others, research has begun with CBD therapies to minimize the discomfort caused by asthma in the respiratory tract, obtaining very good results.


WHAT IS ASTHMA?

If you have ever felt asphyxiation or that the air you breathe is not enough, you know that it is an almost panic situation. Asthma is like that, a chronic respiratory disease that makes it hard for the person to have a good breath. It occurs when the airways become inflamed and narrow, complicating the passage of oxygen to the lungs.

Under normal conditions, by relaxing the diaphragm, the lungs can expand and receive more air. During an asthma crisis, the bronchial tract becomes irritated and inflamed, which can cause the diaphragm to contract, complicating breathing and generating an involuntary hiss when breathing.

The causes of asthma are varied: it can occur due to emotional, environmental factors such as dust, smoke and cold, or also genetic. This disease can be lethal and does not have a specific cure, but with good treatment, the risk decreases greatly. Thanks to its anti-inflammatory properties, CBD is thought to be a natural alternative to treat asthma.

Asthma and its effects on the human body

We already know that asthma is a disease of the respiratory tract. But what does it do in the body? Well, basically, when there is a crisis or asthma attack, the lungs are temporarily reduced, making breathing difficult and even painful. This disease has a strong hereditary component, but it can also be caused by allergenic effects such as dust, certain odours, climatic and even emotional factors.

The first thing that happens when someone suffers from asthma, is the inflammation and from it all the other symptoms are released. This condition is continuous because even when the person feels that he is breathing well and does not have an asthma attack, the airways remain inflamed.

Inflammation also generates hyperreactivity, that is, the high sensitivity of the respiratory passages. That is why when someone is asthmatic, in a state of normalcy, the simple fact of receiving cold air, smelling perfume or a little smoke may cause a great asthmatic reaction. In short: it is unpredictable. Another effect of inflammation is bronchoconstriction, an excessive contraction and usually full of the mucosa, in the respiratory tract.


CBD FOR ASTHMA

The various medicinal properties that CBD has have earned this cannabinoid a growing reputation. In the case of asthmatic people, CBD can help as:

Anti-inflammatory

CBD has anti-inflammatory properties. This is stated because the CBD interacts directly with the receptors of the endocannabinoid system of our body, managing to reduce the levels of inflammation of the tissues. In asthma, tissue inflammations are constant, so CBD can help.

Antispasmodic

Because of its calming effect, CBD is very effective in relieving muscle spasms or bronchospasms that can affect a person during an asthma crisis. For many patients, these spasms are the most desperate situation, so the CBD could fight them.

Expectorant

Although there is still insufficient solid evidence, many cannabis users around the world have indicated that after vaporizing or smoking, they have felt an expectorant effect. This, again, would allow decongesting the airways.

Antibiotic

According to research, asthma can have genetic causes or it can develop due to bacterial infections during childhood, affecting the immune system. Since CBD and CBG cannabinoids have been shown to have broad-spectrum bactericidal effects, they can help with asthma antimicrobial treatment.

Analgesic

However, many patients indicate that their chest hurts when they are in the middle of an asthma crisis. CBD has analgesic effects, so it can relieve the pressure of the lungs and diaphragm, as well as lessen the pain associated with asthma. However, in this case, its use would only correspond to crises.

Contradictory as it may seem, experiences have shown that one of the most recommended options for this treatment is to inhale or vaporize CBD. Why? Because in this way you provide your body with a maximum CBD content that will help you fight asthma attacks more quickly.

You can get CBD oil with different concentrations. You should only talk to your doctor before consuming this product to treat asthma or self-medicate. However, vaporizing this oil has no major negative effects on the lungs or throat. However, if there is any discomfort or the symptoms get worse, it is better to opt for an edible form of CBD.

The main difference between vaporizing CBD and consuming it in another way is that the first option acts more efficiently when an asthmatic crisis occurs. This is because when you vaporize, you take advantage of the CBD at its maximum concentration and send it directly through the airways. Otherwise, you would have to wait for a little before perceiving the therapeutic effects.


The dose of CBD for Asthma

Each person is different and so is their response to CBD. That is why the doses can vary between one individual and another, also depending on the concentration of CBD you are using. Normally, it begins with a low dose, depending on the case of asthma, and if no results are observed, it can be increased if the doctor authorizes it.

As previously mentioned, the best way to consume CBD in cases of asthma is to vaporize its oil, but if for some reason you do not want or can not consume it like this, you can apply it sublingually. You should only apply a couple of drops under the tongue and keep them until they are completely absorbed.

Vaporizing CBD oil, consuming it in the form of capsules or dissolving the drops with a meal, are the easiest ways to control the dosage. Be careful because, although there is no record of any death or serious side effect from CBD consumption, a very high dose can cause certain discomforts such as drowsiness, diarrhoea or vomiting, and even more so if it is the first time you have the tests.

Personal experience

Since I have a memory I was going into the emergency of the hospital from my home town with a very deep Asthma attack, getting an adrenaline shot in my leg, and right after a long blackout, waking up later with my mom or dad in the side taking care of me. While I was growing up the development of my Asthma crisis where continuously, later on with oxygen and salbutamol, once we move to an island in the Caribbean, and that was even worse, I was in the hospital for a week.

Endless treatments and test’s, physical and medical, no one has cured me once for all, I have a very allergic and reactive Asthma type, today I can say is a very annoying problem, some limitations can make my life hard when I can’t get the medicine.

One of the best results where achieved when I decide to make a very strict diet, no sugar, fats, strong or spice food elements, also dedicate my self to training more, swimming, cardio, and mountain bike, the change was impressive, and the efficiency really great, no Asthma for long time, and better style with my normal life.

Researching and practising with different therapies I discover CBD oil, and have noticed when I take it I was available to breathe much better, sleep dipper and have more time between crisis, recently I m drinking 10% RAW ENDOCA CBD OIL soft gel, and 3% RAW ENDOCA CBD OIL drops, I’m very pleased to say than the long term of treatment can give me the perfect results for leaving behind allergies and Asthma attacks, I don’t think it will be only the CBD than will help, but a fundamental ingredient to always have.

How I meet CBD for the first time?

I was travelling to another continent a long trip so, jetlag for a while, 2-3 days after I have arrived went to my friends house for lunch and we talk about it, he told me, I may have the solution for it, “here you go”, and that was a dark brown little bottle with some type of liquid in it, right away I ask him, what is this about, what is in the bottle? “This is a CBD oil 50%, It will help you to get over the effects of the jetlag, take 2 drops and then wait” So I took right away the drops,  after some time I went back home, relax a bit and fall sleep, next day felt fresh, much better and no symptoms of jetlag, ready to roll, so that was my first experience with CBD, and I will go later in this subject about the jetlag and CBD.

Now more committed to keeping discovering their effects on myself making a personal journey about it, and sharing it with you with big pleasure.

References

– Leinow,, L. and Birnbaum, J. (2017). CBD: A Patient’s Guide to Medicinal Cannabis. North Atlantic Books.

– Vuolo, F., Abreu, S., Michels, M., Xisto, D., Blanco, N., Hallak, J., Zuardi, A., Crippa, J., Reis, C., Bahl, M., Pizzichinni, E., Maurici, R., Pizzichinni, M., Rocco, P. and Dal-Pizzol, F. (2019). Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma. European Journal of Pharmacology, 843, pp.251-259.

– Pini, A., Mannaioni, G., Pellegrini-Giampietro, D., Beatrice Passani, M., Mastroianni, R., Bani, D. and Masini, E. (2012). The Role of Cannabinoids in Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke. Current Drug Targets, 13(7), pp.984-993.

– Who.int. (2019). WHO | Asthma. [En línea] Disponible en: https://www.who.int/respiratory/asthma/en/ . 

– WebMD. (2019). Guide to Asthma. [En línea] Disponible en: https://www.webmd.com/asthma/what-is-asthma#1

THE CBG OIL

THE CBG OIL

First described in 1964 by Gaoni and Mechoulam, the CBG or cannabigerol is one of the cananbinoids exclusively produced by cannabis plants in the glandular heads of their trichomes. While the CBG content of most plants is low or very low – in most cases less than 1% – the importance of this compound is crucial for the synthesis of other cannabinoids, as it has been known for 4 decades (Shoyama , Yagi and Nishioka in the journal Phytochemistry, October 1975). Normally, hemp varieties contain higher percentages of CBG than those of narcotic cannabis.


IS CBG A PSYCHOACTIVE CANNABIDIOL?

CBG is a non-psychoactive phytocannabinoid, that is, it is naturally synthesized by plants and does not cause a feeling of drunkenness when consumed. It is attributed multiple medicinal properties that can be used in a wide range of medical conditions, and it is also (its acid form, to be more exact) the precursor of the main cannabinoids secreted in the trichomes, such as THCA or CBDA, which explains the low content in this compound compared to those that originate from it.

It is important to keep in mind that most of the evidence comes from preclinical studies, which means that the safety and efficacy of CBG have not yet been tested in humans. That said, CBG studies have revealed a wide range of possible benefits.


THE GREAT BEFEFITS OF CBG

Stimulates bone formation and healing: The effects of CBG and other cannabinoids on bone marrow cultures were investigated. The results showed that they could stimulate bone marrow stem cells indirectly through the CB2 receptor. This suggests that CBG and other cannabinoids can help the healing of bone fractures by promoting the growth and formation of new bone.

Tumor growth decreases: It was reported that CBD, CBG and CBC along with other cannabinoids slowed the progression and growth of several tumors and cancer cells. By slowing tumor growth, these cannabinoids could extend the lives of people fighting cancer.

Antifungal and antibacterial treatment: The antifungal and antimicrobial properties of various cannabinoids, including CBG, are currently under investigation. CBG proved to be highly effective against MRSA (methicillin-resistant Staphylococcus aureus) in a 2008 study. SARM is a strain of bacteria highly resistant to antibiotics.

Relieves pain: CBG and other cannabinoids are known to have analgesic effects in various conditions, including pain caused by multiple sclerosis and cancer. According to a 2008 article, clinical trials have shown that synthetic cannabinoids are well tolerated and effective, and can have an additional analgesic effect when combined with other pharmaceutical products for pain treatment.

Reduces inflammation: Cannabinoids such as CBG have the ability to reduce inflammation by targeting specific molecules responsible for inflammation in various disease states, including symptoms of pain, cancer and even inflammatory bowel disease. For example, studies show that CBG can act as a COX-2 inhibitor, similar to widely used medications called nonsteroidal anti-inflammatory drugs (NSAIDs).

Treatment of overactive bladder: Cannabis and cannabinoid preparations have been used to treat various bladder dysfunctions. In a 2015 study, researchers tested the effects of CBG and other cannabinoids on experimentally induced bladder contractions. It was found that CBG and THCV had the strongest capacity to reduce bladder contractions.

Psoriasis and skin treatment: CBG and other cannabinoids may be useful for treating various skin disorders, due to the presence of cannabinoid receptors in the skin. In a 2007 study, CBG was shown to inhibit keratinocyte proliferation, which suggests a role for CBG in the treatment of psoriasis.

Glaucoma treatment: In a 1990 study, treatment with THC and CBG increased aqueous flow two to three times in animal models of glaucoma. Increased water flow can help reduce intraocular pressure in cases of glaucoma.

Depression and anxiety treatment: It is well known that THC can help patients suffering from depression and anxiety. It has been found that CBG has similar effects, but without causing the psychopropic effect that THC is known for. A 2016 report suggests that non-psychoactive cannabinoids such as CBG could be a possible alternative to treat anxiety and depression.

 

Neuroprotective effects: In a 2015 study on animal models of Huntington’s disease, it was discovered that CBG is “extremely active as a neuroprotective.” CBG treatment improved movement and recovery in mice with Huntington and neurons protected against degeneration. The CBG also showed possible anti-inflammatory and antioxidant effects. The researchers concluded that CBG should be studied further as a treatment for neurodegenerative disorders.


CBG IN ANOTHER WORDS AND CANNABIDIOL WORLD

CBG is the basic component for many Marijuana compounds, including THC and CBD. Cannabinoids are the active chemicals found in Cannabis. They are plant specific and are known to affect the human body in many ways. While you may have heard of cannabinoids such as THC and CBD, not many realize how important CBG is when it comes to Marijuana.

CBG is not psychoactive and can be considered as the “stem cell” or “progenitor” of other cannabinoids.

After being synthesized, CBG quickly converts to other cannabinoids through natural processes that occur within the Cannabis plant. This explains the low CBG content of most Marijuana varieties.

More CBG has been found in hemp than in cannabis, so it is thought that this variety has a recessive gene that stops the production of synthases, the enzymes responsible for CBGA breaking down and evolving into another cannabinoid. This discovery about the absence of synthases in hemp means that new hybrids can be made to create genetics that are richer in this cannabinoid. There are already some seed banks that offer strains with a higher proportion of CBG, the result of hybridization of different varieties.


Commercial interest:

As research on CBG progresses, this is undoubtedly making its way to the top positions of curative cannabinoids due to the enormous potential it shows in studies, hence the market for varieties with higher concentrations of this CBG molecule whether they are of great commercial interest and be the new trend in the cannabis market.
A high demand for THC-free and high-CBG products is expected. Currently, only a limited number of companies offer high quality CBG seeds and that creates a huge opportunity.
A seed of a variety of hemp free of psychoactive components with high CBG, makes it unique in the market, with highly medicinal properties and far from any bureaucratic and / or legal obstacles. At the same time, it allows the possibility of opening up to any possibility of products such as oils, biomass, flowers, edibles, extracts, topics, drinks, concentrates, tinctures. In extractions, the CBG requires less purification than, therefore, the costs are lower. It has a strong economic performance, producing surprisingly productive crops, allowing a better evaluation of its medicinal properties, under optimal cultivation conditions. Finally, revenues are much higher than in the case of CBD.


 

Coclusion:

In this new world where all and every day is putting on test so fast, we have to consider the facts than less invasive to the body and system the best results will be achieved, CBG is one of the most primary forms of cannabidiols, this make the resonance of the most natural source where the cannabinoid system can connect easily, there is a lot to discover, evidence is showing at every minute, day after day CBG isa proving solution for health obstacles, less invasive, far way from over dosis, is getting very popular in the understanding of what will be the best product to keep and not be ignored. The particular amount of CBG than you can take out of the plant is around 1%, so is not very large the amount. In any case the oils we are going to study in the deep it will be CBG, this external cannabidiols are making a great effect, is important to understand that to get the real stuff you must consider to read the labels and to make a research over the brand you are about to purchase, one of the important stuff will be if there is a 3rd lab tested, another important is to know if the product itself is organic, the package, the price. Is also very interesting if you find the flower of the CBG string, the review I have found are very positive regarding the effect, the look, smell, and the after smoke feeling, some of them says it feels like a great deal of calmness and relax, NOT hight or stone, but with a very particular relaxing stage. In many countries still not legal to use any of the cannabidiols, we are getting close in to an end of regulations, I am afraid than the big players haven’t start to have presence in the cannabidiols market as they shut, and probably when they arrive will be a lot of regulation and vanish the small brands, or the ones who are not available to sustain a good product in the whole concept of what is coming, I must say, than in another hand is good, because is a lot of crap and bad business only printing money and not carrying for the end consumer. I will came with a project of CBG in a very narrow way to help myself with inflammation and stress, thanks for your time ad I wish you a great weekend and life, big love to you all.


REFERENCES

Cannabis and cannabinoids-easier access, hype and disappointment : What has been confirmed in therapy?]Rasche T, Emmert D, Stieber C, Conrad R, Mücke M.Internist (Berl). 2019 Mar; 60(3):309-314.

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Fitzcharles MA, Ste-Marie PA, Hauser W, Clauw DJ, Jamal S, Karsh J, Landry T, LeClercq S, McDougall JJ, Shir Y, Shojania K, Walsh Z. Efficacy, tolerability, and safety of cannabinoid treatments Care and Research. 2016.

 

 

THE ENDOCANABINOID SYSTEM

THE ENDOCANNABINOID SYSTEM


The first evidence of its therapeutic utility dates back to
reign of Emperor Sheng-Nung in China (year 2737 BC), who collects in pharmacopoeia manuscripts its usefulness for treating cramps, rheumatic and menstrual pain.

In ancient Egypt, numerous papyri also describe the administration of cannabis preparations in the treatment of various ailments.

But in Europe, it is not until the nineteenth century when cannabis becomes a common medicine and legal use for its usefulness in the treatment of pain, seizures, spasms and emesis. However, in 1925 the Genoa Convention includes cannabis and hashish in the list of illegal and dangerous drugs.

Cannabis sativa contains more than 460 different chemical compounds, of which more than 60 are grouped under the term “cannabinoids”, which refers to substances that have a carbocyclic structure of 21 carbons. In 1964, Gaoni and Mechoulam isolate and determine the structure of the principal responsible for the psychoactive properties of the plant, ∆9 -tetrahydrocannabinol (∆9-THC), and in 1988, Devane et al. discover the specific receptor of this cannabinoid, the CB1 receptor. These findings have allowed to discover and characterize in the last 20 years an endogenous signaling system known as the endocannabinoid system. This system exerts its modulating role mainly in the brain but also in the periphery, and consists of receptors, ligands (endogenous, phytocannabinoids or synthetics) and enzymes responsible for their synthesis and degradation.

The human body is a very complex machine; We still don’t know how it works completely. One of the body’s systems that has been receiving a lot of attention lately, is the endocannabinoid system, and the way in which CBD interacts with it.

When it comes to things like stress, anxiety, pain and inflammation, people generally think that the brain’s neurotransmitters, and the central nervous system, have a monopoly on them. However, research has discovered another system that plays an important role in the regulation of these emotional and physiological states. This system is the endocannabinoid system. Today we are going to take a look at what it is, and how it interacts with the CBD.

WHAT IS THE ENDOCANABINOID SYSTEM?


The endocannabinoid system is a network of receptors that extend throughout the body, practically all the parts reached by the central nervous system. As the name implies, the endocannabinoid system is what the many cannabinoids found in cannabis interact with. In addition, and it is quite interesting, regardless of the natural equivalents that the body produces by itself, there is no other natural source of cannabinoids apart from cannabis. It is believed that the endocannabinoid system plays a very large role within the body, as research indicates that it is also involved in the regulation of the immune system, inflammation and many other processes – in addition to those already mentioned in the introduction.

THE CBD AND THE RECEIVERS


The endocannabinoid system is composed of a network of receptors of two types. CB1 and CB2 receptors. Unlike THC, which can bind to CB1 receptors, CBD cannot bind to anyone perfectly. The result is a stimulated activity without a link occurring. This means that any cell that contains a CB1 or CB2 receptor will change by interaction with the CBD, and since these receptors are found in virtually every part of the body, including the brain, the effects of the change occur throughout the system. This method of interaction is to a great extent to be thanked for the effects they feel when taking a CBD supplement.

If something is showing us cannabis research, we still have a lot to learn about the human body. The study of cannabis continues to find new and interesting ways in which we can potentially benefit from this extraordinary plant, with CBD and the endocannabinoid system being one of its main themes.

The endocannabinoid system plays a very interesting and varied role within the human body. A decade ago, it was believed that the brain and the central nervous system were the main driving forces responsible for conditions such as stress, anxiety, inflammation and pain. Although this is not disputed, more recent research indicates that there is a third party that also participates in the fight against these conditions: the endocannabinoid system.

 WHAT IS THE ENDOCANNABINOID SYSTEM?


In its most basic form, the endocannabinoid system is a network of receptors that extend throughout the body – almost in the same way as the central nervous system. These receptors interact specifically with cannabinoids, creating the effects that result from the use of marijuana. But it is not only designed to place you. Studies have shown that there is very positive evidence that the endocannabinoid system is essential for the regulation of many bodily functions. This includes aspects such as the immune system, inflammation, pain and energy homeostasis – to name a few. Also, interestingly, apart from the natural equivalents of the cannabinoids produced by the organism, there is no known other natural source of cannabinoids than marijuana. It is as if it were your destiny!

Although the endocannabinoid system is the main point of interaction with CBD, it is not the only one. So we believe it is worth mentioning quickly the other ways in which CBD interacts with the body. This additional interaction is caused by CBD stimulation on other receptors. For example, CBD is believed to activate serotonin receptors. It also stimulates G protein receptors that affect temperature control and pain perception.

The endocannabinoid system is important for your health and balance in general, but its importance is that the medical community has not understood it until recently. It is through this system that the natural cannabinoids of CBD oil interact with our bodies and trigger their many beneficial effects. Because of the way it affects the way our bodies function, a healthy endocannabinoid system is essential and it is essential that we learn how to maintain it.

THE ENDOCANABINOIDS AS THEY REACT IN THE BODY


Endocannabinoids are created in response to the needs within the larger physiological system and are used for the body’s regulatory functions. They act on presynaptic cells to control the volume to which communication signals are sent. This is how endocannabinoids affect the duration and intensity of the wide range of physiological processes under its control.

RISK OF OVERDOSE WITH CANNABINOIDS


While the endocannabinoid system is linked to several important processes and is concentrated in the brain, nervous system and reproductive organs, it does not affect the regions of the brain that control cardiac and pulmonary function. This feature is one of the main reasons why fatal cannabinoid overdoses do not occur.

ENDOCANABINOIDS FOR THERAPEUTIC PURPOSES



Dronabinol and nabilone are two CB receptor agonists that are currently in use. So are Sativex, which is a cannabis extract, and rimonabant, a CB receptor antagonist. Both are synthetic cannabinoids that have limited scope as therapeutic elements.

 

It is the phytocannabinoids, coming from the whole plant, that are offering better results, thanks to the entourage effect that the rest of its elements carry, such as flavonoids and terpenes.

The use of cannabinoids for therapeutic purposes is still under investigation in many countries. However, in the pharmacies of the Netherlands, it is possible to acquire raw cannabis. In this case, cannabis is regulated and its production is controlled and supervised by the Dutch Ministry of Health.

In countries like Spain. Belgium and some regions of Switzerland also tolerate the therapeutic use of cannabis in small doses. Also in the United States, some states have legalized the medicinal use of cannabis and in Canada, citizens have the possibility of using cannabis for therapeutic purposes as long as it is purchased in the indicated establishments previously established by the government.

The use of cannabinoids for therapeutic purposes remains a great unknown in medical consultations and among alternative medicinal treatments. However, the cases mentioned in countries in Europe, the United States and Canada demonstrate that the use of cannabinoids can have successful medicinal effects.

CONCLUSION AND PERSONAL EXPERIENCE


Understanding that the endocannabinoid system is within the evolution of the mammal kingdom we can simply deduce the need to keep it active, every day more in our environment we are exposed to interaction with the environment of various types, where we are encouraged to use our energy for survival, healing process, recovery, enjoyment and degradation over the years. Now, how can we maintain stable health over time? How can we overcome the threshold of fear and find natural solutions for our moments of life and carry out a whole routine of life without so many difficulties? The answer every day is clearer, and it is about the CANNABINOIDS and their interaction with our homeostatic system and the endocannabinoid system, which is none other than the one that regulates the entire physical-chemical balance with which we can cope with daily life, it is precisely with which we connect to the nature from which we come as part of the animal kingdom, as part of the universe.

I have personally been able to experience it, and it is one of the most elusive sensations that I have lived, which is why I have had this initiative regarding this fascinating project and my connection to the world of CANNABINOIDS, the sensation of being able to feel a quick relief, comforting, natural, fast and effective solution to my personal health problems has been fabulous, it has given my body the necessary time to recover and heal learning from their own abilities, I have one more universe to discover, each day continuing and making this passion an inspiring role model for all who want to get into this knowledge and experience.

REFERENCE AND SOURCES


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CBD SPORTS AND TRAINING

CBD, INITIATOR, ENDURANCE AND RECOVER

Athletes will come using the CBD in some way in different ways to help their training routines. When consumed as an oil before exercise, this cannabinoid improves performance.

After doing sports you can improve recovery. For all this, this substance can become a supplement among the essential for elite athletes.

CBD as a compound of medical marijuana

CBD or cannabidiol is an element present in some of the various varieties of marijuana. It is one of the more than 545 compounds that are part of the chemistry of Cannabis Sativa, the most widely used type of medical cannabis.

If you have seriously practiced a sport in which your resistance is tested, you will know how hard it is. It affects your muscles, leaving them sore muscles, and also influences your immune system.

Instead, suppose you are a professional athlete, performing as an athlete and constantly changing your body beyond its limits. Training of such intensity always ends up taking its toll.

FULL POWER AT THE EXTREME

A situation that becomes even more alarming if you practice contact sports, such as rugby or boxing, for example.

Getting over it is a necessity, but the consumption of any type of drugs is a problem in the professional field. Opioids and steroids are part of the concern.

However, in countries like the US This is the pain reliever included for chronic pain derived from professional sports, while, thanks to the anti-drug fight, doping controls include cannabis.

If it is detected in any type of athlete’s body fluid, it can be considered a reason for sanction.

Athletes face regulatory norms against marijuana in any sport, in all countries, being difficult to foresee a future change of situation.

For example, the National Football League is currently facing the issue, and changes may be suggested soon.

When you play sports, your body produces chemicals naturally, the so-called endorphins. You also generate something known as anandamide, a neurotransmitter that we usually consider the “happiness molecule.”

Anandamide, due to its functions, could be considered as an endocannabinoid, that is, a natural cannabinoid that is produced in your own organism.

This is why cannabinoids, including CBD, adhere to the receptors without problems. When anandamide is attached to a cannabinoid receptor, it initiates a calming effect.

This may be something that does not seem effective in subjects with high levels of anandamide. In contrast, for those who suffer from low levels of anandamide and need additional energy, this substance has effects incomparable to those of other medications.

The CBD interacts with the TRPV-1 receiver. This type of receptors is involved in the perception of pain, inflammation and body temperature.

In addition, it activates the adenosine receptor, a function that is essential for the functioning of the cardiovascular system and blood flow.

Many athletes have discovered the benefit of marijuana with CBD over their exercise rhythms. And later, especially when applied as an oil on the skin, it helps to make recovery faster.

CBD help your body recover and maintain a better homeostasis.

It is a product with very few or no adverse effects. It lacks psychoactive properties, but enjoys many therapeutic-type virtues, making it a powerful ally in the medical field. Therefore, scientific research on the compound has been intense over recent years.

The road to the legalization of CBD in sport

It is true that it is quite simple that some dependence on an opioid is generated, and that there is also a high risk of overdose. In addition, it is common for the consumer to understand the difference between a dose with palliative function and another that could be lethal, and do so before it can be too late to ask for help.

Therefore, and especially in this time of reforms, football players are beginning to unite in order to claim that cannabis be included in the list of substances allowed in the sport.

 

NFL AND ITS REBEL FIGHT IN FAVOR OF CBD

In this circumstance is the aspect of greatest interest about this new rebellion in the NFL. There are several sports institutions that are currently valuing the influence of cannabis on physical performance.

At the moment it is still prohibited, and athletes continue to undergo all tests for detection.

These controls contemplate much more than the consumption of THC (the main psychoactive constituent of cannabis).

The position in the American league is that, in practice, even when using some kind of oil with CBD on the skin for the treatment of mere muscle strains, a player could be exposed to a penalty for drug use.

In the NFL all this has become a problem for both players and owners of all teams. But there is hope.

In three years the collective agreement will be renegotiated, and there is a forecast that prohibitions on cannabis will be removed from the league from that date.

This could also cause a chain reaction in the regulations of many other sports institutions and organizations. And we will surely see it in all kinds of fields, starting from the very Olympic Games and going through soccer or long distance athletics to cycling.

There is no doubt that this situation is leading to a new revolution. Medical marijuana, with high contents in the CBD compound, is on the eve of entering fully into the sports field, ceasing to be an exclusive medicine for patients and patients.

There is a long way to go, and its acceptance will be progressive, but it will not take long to see how this complement is used in a normalized way in sport.


WE ARE SEEING A NEW CLASS OF ATHLES EMERGE: THE ENTHUSIAST

There is a long list of supposed benefits associated with marijuana, but some say it can also help improve endurance during a workout

Some athletes, such as former NFL linebacker Eben Britton, have been open about the perceived benefits of marijuana to stay fit, but there are still many who are “in the closet” due to the stigma of drug use.

Historically speaking, fitness and marijuana have never been considered the best training partners. In fact, you probably considered them as opposite poles. In one corner, you were aware of health and fitness; in the other, the drug addicts and their monchis.

But as cannabis laws have relaxed (medical marijuana is now legal in 29 states, while recreational marijuana is legal in nine), we see a new class of athletes emerge: the marijuana enthusiast.

“It has become a social movement,” says Jim McAlpine, founder of the pot-friendly 420 Games athletic event series, as well as the San Francisco-based Power Plant Fitness gym, which is co-owner of the former NFL. Ricky Williams runner. “There are so many of us that we are in the closet.”

 

McAlpine, Williams and their henchmen are part of a new generation of cannabis users, who enjoy a highly fitness lifestyle, even though they smoke pot.

Pro Marijuana athletes tend to brush cannabis for several reasons. “Activate your brain and take you to The Zone,” says McAlpine. “I love smoking before skiing, riding a mountain bike or going surfing. It puts me in a place of less focus, the kind of? Eye of the Tiger ?. It’s not for everyone, but for some people who are more athletic and coordinated, it works. ”


GAME CHANGER

While coordination and concentration may not be the first things that come to mind when you think about the potency of marijuana, McAlpine is not alone in his belief that going on before training can perfect an athlete to be fit. According to former NFL offensive lineman Eben Britton, who has spoken openly about NFL players who use cannabis to control pain, smoking marijuana “connects me mentally and emotionally to my body, allowing me to exercise more satisfying. ”

Smoking cannabis before training helps relax stiff muscles and scar tissue, as well as your mind. “It’s very encouraging mentally. It allows me to get the last two reps,” he told MensHealth.com. “I may be getting tired, but it puts me in a state of flux and allows me to move on.”

If you are skeptical about the benefits of marijuana’s physical condition, you have reason to be. For years, marijuana has been promoted as a treatment for everything from epilepsy to opioid addiction and sleep apnea, so it is not surprising that some athletes swear that it could also help them improve their performance.

 

 

That said, there is little evidence to suggest that smoking before a workout can, in fact, increase your earnings. “It has been shown that cannabis is a drug that degrades performance, so for maximum performance you should not use cannabis,” says Jordan Tishler, a doctor and specialist in cannabis therapy trained at Harvard. If you are smoking marijuana before a new or particularly difficult training, it can be downright insecure: according to the National Highway Traffic Safety Administration, “the more difficult and unpredictable the task, the more likely it is that marijuana impairs [mental and motor] performance.” .

But this is where the supposed benefits come in, says Tishler: “cannabis has proven to be good for pain control and can be useful while training at standard levels. Like a runner, cannabis can help with resistance “.


MEDICAL CANNABIS

The cannabis doctor, Dr. June Chin, agrees. Whenever an athlete is not injured or at risk of injury, She often suggests that She use cannabis “during the training season to help recover, relieve pain and move to the next level. The goal is not to stop with that knee. stubborn or low back pain. They can run the longest distance, be faster and more efficient. They can drive you. ”

The evidence is particularly strong for CBD (cannabidiol), a non-psychoactive compound in marijuana (for example, it doesn’t make you very? High?) ​​That many athletes claim to improve recovery. After his UFC fight with Conor McGregor, Nate Diaz was bloody and bruised, but relaxed, he sat down for a press conference and launched CBD steam, telling reporters he “helps with the healing process. That unlish a great debate about the uses in sprts and make a radical change in the sports world.

 

 

THE PERSONAL EXPERIENCE

Nowadays I’m training not very much than before but indeed more than what I really spect, having a newborn, learning in a  new country and culture and do not forget about a new language.

So I started taking CBD OIL 3% RAW from, from a company named ENDOCA, in the first experience opening the box and finding the little bottle, in the packaged was not doses suggestions, so I did have no idea how to take it, well, I went into internet and land with my research in a yahoo page and was some guy than want to try CBD OIL for a week, so I check it out and this young dude starts with a very hi doses, like 30ml per day, and I was like really surprised, but I said to my self, no play no game, let’s do that, so I got a full pipet with the oil and took to of them full up, and then climb on my bike and when directly to the gym.

When I got there nothing happens, I feel nothing in special, after in the warming up stage I was, as usual, very rising my cardiac frequency, feeling the anaerobic taking place, nothing relevant to say so far.

So I jump into the other stage of the training routine, that was lifting, pushing and muscle pumping, medium weight to a decently heavy, I use to combine in the recovering time with some abs crunching and then I starting feeling a bit different, my esqueletong felt more elastic, and my capacity increase in a huge abundance, I was so fresh, active and wanting more, the oxygenation was remarkable more effective, so I reach a level than never happen before.

Now we are in process of creating a formula for athletes, I’m working directly with organic hemp producers and a certified CO2 extraction company, based in Europe, where they love to do things right and looking deep in details.

Working directly with different ages and sports disciplines, the results so far are really stunning.

2 doctors are develope the products and the products are working very well in front the, we also have athletes in MMA Fighting and Pro Wrestling also my partner a professional Rock climber how is taking the whole protocol and taste it the field, the reactions and feedback are insane and they are anti-doping tested ..so everyone can use it

Rock climbing

Crossfit

Gym training

Swiming

Aerobics and anaerobic

So imagine if you can increase your power, endurance and recover faster and more effective than never before?

In the next weeks, we will make more announcements about this unique experience.

Thanks to all, love to all.

 

Dr. Aref Souki

 

DISCLAIMER
This publication was written with only one purpose to inform and send our dear visitors one more opinion about the fascinating world of the Canabidiols and their possible alternatives, we must take into account that the information published here is mixed, both from external sources, as well of own authorship for some notes and general points of view.

MEDICAL CANNABIS AND THE POWER OF WOMAN

Cannabis in obstetrics and gynecology

Women consume cannabis for therapeutic purposes since ancient times. Today, science indicates that THC and CBD could be safe alternatives to treat many gynecological conditions. Read on to find out about current research and how cannabis derivatives can help women throughout their lives.

The use of medical cannabis and women’s health have been related since the man knows the herb. The use of cannabis in ancient obstetrics and gynecology seems to reveal a connection between the nature of women and the uniqueness of the female flower of cannabis. Throughout history, cannabinoids have acted as great allies in various diseases related to our complex reproductive system. And today, the growing cannabis market offers oils, bath products, capsules, topical creams and even buffers with THC, CBD or a combination of both cannabinoids.

THE CANNABIS AND THE HISTORY OF GYNECOLOGY

Archaeologists discovered references to the use of medical cannabis for women’s health in texts from ancient Mesopotamia from around 2000 B.C. At this time, the herb was mixed with other plant substances to treat menstrual pain, and since then, women around the world have consumed weed for many reasons. This fragrant plant was included even in the Egyptian pharmacopeia, where it is mentioned many times in the medical texts of ancient Persia, and was consumed by women from all over the Mediterranean and Europe. The same happened in India and in the Chinese Empire, as indicated in a detailed historical analysis conducted by Ethan Russo.

The herb used to be administered through methods quite similar to those currently used: orally, rectally, vaginally, topically and by fumigation (when inhaling the smoke from the burning of cannabis flowers). We can find clear descriptions of these methods in ancient medical texts, with specific references to gynecological symptoms and diseases to be treated. Among these conditions are painful cramps, bleeding, infections, swelling, menstrual disorders or menopausal symptoms. Cannabis also helped relieve contractions and facilitate the process of childbirth, but it was also used to cause abortion. This is a particularly enigmatic aspect.

CANNABIS IN GYNECOLOGY BEFORE PROHIBITION

During the 19th century, cannabis derivatives were included in official pharmacopoeias to treat a wide range of diseases, and their use in gynecology was recommended by the leading eminences of medicine, as well as Queen Victoria. This intelligent queen was also the Empress of India, where many herbs and natural remedies came from. Centuries after his death, she became famous in the cannabis community worldwide, as it was discovered that she used cannabis tincture to relieve his menstrual cramps.

Irish physician William Brooke O’Shaughnessy continued Queen Victoria’s line by validating traditional cannabis use in India, discovering new applications and recommending cannabis extracts for a wide variety of therapeutic purposes. O’Shaughnessy noted the effectiveness of cannabis in reducing uterine bleeding, and in the mid-1900s, doctors promoted cannabis tinctures for menstrual conditions and other diseases of women. A new branch of clinical research on cannabis was being initiated where women’s health was included, but then the ban came and everything changed.

THE RENAISSANCE OF CANNABIS IN THE HEALTH OF WOMEN

After the dark era of the ban, which today is not much brighter, the science behind centuries of anecdotal data was beginning to be confirmed thanks to a great deal of new research.

Endocannabinoid system

(ECS) It is a very important regulatory network with functions related to mood, metabolism, appetite, immune system response, memory and pain perception. Ultimately, one of the main tasks of the SEC is to help the body maintain a state of internal balance known as homeostasis.

The ECS plays a role in female hormonal balance and in reproductive processes. Cannabinoids derived from cannabis are capable of interacting with the cannabinoid receptors of our body, and this is where “magic” arises.

MENSTRUAL PAIN

Today, we have strong evidence on the properties of cannabis to relieve pain, both in clinical studies and in patient experience. The research also confirms the anti-inflammatory effects of cannabis derivatives, which can help reduce pain. Today, more and more women consume cannabis in various ways to treat Painful symptoms such as uterine inflammation and other problems related to menstruation.

Despite that, there is no rigorous study that has investigated the properties of cannabis against nausea during a woman’s menstruation. That said, THC is famous for its antiemetic properties, and the compound has been involved in the treatment of chemotherapy for years. Research on the specific effects of cannabis on menstruation pain is also lacking, but it has been found that the interaction between THC and estrogen provides greater pain relief. This result leads to the conclusion that cannabis could be more effective in relieving pain in women than in men.

PREMENSTRUAL SYNDROME

There is very little research available on the effects of cannabis on premenstrual syndrome, despite the known benefits for pain, muscle tension, headache and mood. Women who live in areas where cannabis is completely legal are more likely to try products that contain THC and CBD when it comes to relieving premenstrual syndrome symptoms related to mood. In most of the world, CBD products can be consumed as a home treatment for the conditions mentioned above, including anxiety and mood disorders caused by premenstrual syndrome.

ENDOMETRIOSIS

Endometriosis is a fairly common and painful health problem that causes the internal tissue of the uterus to grow elsewhere, generating severe pelvic pain, scarring and risk of infertility. Endometriosis affects approximately 1 in 10 women worldwide during their fertile years.

A recent online survey showed that Australian women with endometriosis who consumed cannabis flowers or extracts, CBD oil, applied heat and made changes to their diet, were the most successful in terms of pain reduction. Physical interventions such as yoga, stretching and exercise were rated as less effective. Despite these findings, the most common remedy for endometriosis pain control is still anti-inflammatory medications, although they have considerable side effects.

SEX

One study showed that 68.5% of women who used marijuana before sex had a more pleasant experience. In most cases, women who consume small amounts of cannabis experience an increase in sexual desire, while higher doses of THC have a negative effect. The positive effect of cannabis on anxiety can also be reflected in sexual life, and also has the capacity to increase physical sensitivity. Although cannabis use during sex has always been popular, research has not provided clear evidence of how sexual experience improves. And it is not an easy task.

However, new health care companies involved in the legal cannabis business have been developing products with cannabinoids aimed at improving sexual life. These products contain THC, CBD, or a combination of both, and come in the form of lubricants, creams, soothing oils, suppositories and, of course, a large number of sweet aphrodisiac edibles. Consumer opinions are largely positive, particularly with regard to pain reduction during or after sex.

CANNABIS FOR MONTHLY DISORDERS


Medicine prior to industrialization considered that “Indian hemp” had a great capacity to increase uterine contractions during childbirth, while also being beneficial against bleeding. There may still be a lot left for us to see edibles or vaporizers in the delivery room, but it is something worth to explore.

The Washington University School of Medicine in Seattle has initiated a study recently called “The Moms + Marijuana Study. For the first time, researchers are trying to assess whether cannabis use to relieve prenatal nausea is safe for baby’s development. The results, which will include images of the brain of the developing fetus, could change the way cannabis is perceived in the medical community.

Women who go through menopause experience several symptoms, many of which are difficult to treat directly. More and more clinical and anecdotal evidence suggests that cannabis, and in particular CBD, has the potential to relieve some symptoms of menopause. Research has shown that the endocannabinoid system regulates, among other things, mood, sleep and pain perception. There is also scientific evidence on the complex role of the endocannabinoid system (ECS) in female fertility, and researchers establish a clear relationship between estrogen hormones, endocannabinoid anandamide and ECS functions.

In addition, laboratory research argues that cannabinoids may help regulate bone development, reducing the common risk of postmenopausal osteoporosis. Research indicates that CBD can bind to bone cell receptors, which inhibits the deterioration process and slows the loss of bone density. Despite the lack of conclusive evidence, cannabis use even during menopause can help the endocannabinoid system maintain homeostasis.

Although an adequate combination of THC and CBD could be more effective for menopause problems, it has been shown that CBD is effective on its own in treating sleep problems and menopausal mood, without exerting intoxicating effects. THC.

REDISCOVERING CANNABIS CONSUMPTION AMONG WOMEN

Unfortunately, studies show that women develop a tolerance to cannabis faster than men and suffer more adverse effects from possible withdrawal symptoms. It also seems that cannabis use affects more women than men in the region of the brain that controls “spatial memory. But on top of that, like any other substance, cannabis has mild side effects and may not work for everyone.

Although most people can safely test CBD, greater caution should be taken with the intoxicating cannabinoid, THC. In legal markets, seeds or products containing a ratio of 1: 1 of CBD: THC, or only CBD with almost no THC can be obtained. Those who want to consume THC can also try microdosing, that is, take small doses of THC throughout the day, without getting “placed.” This should also provide benefits such as relief from inflammation and pain, but without significantly affecting the mind. On the other hand, those who are very familiar with THC can choose from a large number of strains.

Finally, a survey of US women. Published in Obstetrics and Gynecology in June 2019 demonstrates cannabis use among women, backed by a large amount of anecdotal data. Of the 1,011 women with an average age of 37 years, 36% reported that they consumed it to treat a specific condition, such as pain, depression or anxiety. Of these women, 16% said they used cannabis to treat a gynecological discomfort such as menstrual cramps. In addition, most of the women surveyed considered cannabis use to treat a gynecological condition.

References

Russo, Ethan. (2002). Cannabis treatments in obstetrics and gynecology: a historical review. Journal of Cannabis Therapy.

Women and cannabis: medicine, science and sociology – Cannabis Therapeutics Magazine, Dr. Ethan Russo

Brents LK. Marijuana, the Endocannabinoid System and the Female Reproductive System. Yale J Biol Med. 2016;89(2):175–191. Published 2016 Jun 27

Women and cannabis: medicine, science, and sociology – NLM Catalog – NCBI https://www.ncbi.nlm.nih.gov

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects https://www.ncbi.nlm.nih.gov

Effects of Medical Marijuana on Migraine Headache Frequency in an Adult Population. – PubMed – NCBI https://www.ncbi.nlm.nih.gov

Studies on CBD and Anxiety https://www.projectcbd.org

Studies on CBD and Depression https://www.projectcbd.org

Cannabidiol as a Potential Treatment for Anxiety Disorders | SpringerLink https://link.springer.com

DISCLAIMER

This publication was written with only one purpose to inform and send our dear visitors one more opinion about the fascinating world of the Canabidiols and their possible alternatives, we must take into account that the information published here is mixed, both from external sources, as well of own authorship for some notes and general points of view.

CBD OIL AND ANXIETY

CBD AND SYMPTOMS OF ANXIETY?

It has been very promising in its treatment. The human body produces its own cannabinoids, called endocannabinoids, aided by the consumption of fatty acids found in foods such as fish, nuts and seeds. The studies affected that CBD is able to interact with the body’s endocannabinoid system. The endocannabinoid system is a network of mobile receptors and molecules that help regulate human functions such as mood, appetite and sleep. By binding to specific receptors in the human brain, endocannabinoids increase the action of serotonin, a neurochemical that improves mood and relieves stress.

 

BRAIN

How does CBD combat the symptoms of seasonal affective disorder?

The winter months bring short days and less sunlight, factors that can contribute to seasonal affective disorder, also known as SAD. We now know that CBD could fight your symptoms, such as anxiety and sleep problems.

Winter brings shorter days, less exposure to sunlight and colder weather. Some people love winter and love the nostalgia of snuggling between blankets while they drink hot drinks. However, these environmental changes can profoundly and negatively affect some people, leading to a decrease in mood, feelings of sadness and depression. This phenomenon is known as seasonal affective disorder (SAD) and is considered a major depressive disorder. The APR can be treated through several lifestyle factors, such as a healthy diet, physical exercise and a good sleep cycle. Some patients take antidepressant medications. The compounds present in cannabis plants are also being investigated for their possible effect on the symptoms associated with SAD.

WHAT CAUSES THE SEASONAL AFFECTIVE DISORDER?

For now, the causes of SAD are unknown, but it is believed that it is partly due to the decrease in exposure to sunlight. Sunlight is essential for the health of the human being, on which it exerts numerous positive effects, from favoring the assimilation of vitamin D to marking the circadian rhythm or sleep-wake cycle. It is believed that the lack of sunlight prevents a part of the brain, known as the hypothalamus, from functioning properly. The hypothalamus is a gland that plays a crucial role in the endocrine and nervous systems, and is involved in the regulation of body temperature and the release of hormones.

Hypothalamus dysfunction could affect the production of melatonin, a hormone released by the pineal gland to numb the body. Blue light inhibits the production of melatonin, and lack of light leads to an increase in the production of this hormone. Therefore, people with SAD have a high level of melatonin during the darkest months of the year, which translates into a frequent feeling of tiredness. This alteration of the function of the hypothalamus could also affect the production of serotonin, a neurotransmitter that has a very important role in the regulation of mood, appetite and sleep. The decrease in sunlight can lead to a very poor synthesis of serotonin, which contributes to moodiness and depression.

CBD AGAINST ANXIETY

Anxiety is perhaps one of the most prevalent mental disorders in modern societies. In this context, research on the anxiolytic properties of cannabidiol or CBD acquires great importance.

The review of the legality of cannabis and its components in certain parts of the world is a more than anecdotal phenomenon: it is a trend that is also stimulating scientific research in a field as promising as cannabinoids.

 

 

 

 

 

 

 

In a 500-page report by the National Academy of Sciences, Engineering and Medicine on the health effects of cannabis and cannabinoids, it was determined that there is “strong evidence from randomized controlled trials to support the conclusion that cannabis or cannabinoids are an effective treatment “against chronic pain, nausea and vomiting, spasticity associated with multiple sclerosis and other conditions.

On the potential of cannabis to treat anxiety, although the evidence is limited according to the report, it is enough to suggest the convenience of continuing to investigate in that direction.

The report cites one of the most reliable studies on the medicinal use of cannabis, consisting of a systematic review and meta-analysis of 79 trials, one of which investigated the ability of the CBD to reduce anxiety, finding that the CBD was more effective than the placebo.

THE GREAT POTENTIAL OF THE CBD AGAINST ANXIETY

Neurotherapeutics published in 2015 a report “to determine the potential of CBD against anxiety, that is, as a treatment for anxiety-related disorders”, finding that “CBD has considerable potential as a treatment for multiple anxiety disorders given its anxiolytic, panicolitic and anticompulsive properties, as well as a decrease in the conditioned expression of fear, the increase in the extinction of fear, the blockage of reconsolidation and the prevention of the long-term anxiolytic effects of stress ”.

Although the report suggests “the need for additional studies of chronic and therapeutic effects in the relevant clinical populations,” it seems that CBD could not be profiled against anxiety, but also as a remedy to reduce the severity of seizure attacks. Panic, fear and stres.

 

CBD can be outlined as a complementary treatment to help reduce the consumption of other medications whose side effects can range from annoying to devastating. In 2016, a study evaluating the response of a 10-year-old girl with post-traumatic stress to a treatment with CBD oil found promising results. Before the age of 5, the girl had suffered sexual abuse and abuse, and began receiving drug treatment that, in the best case, produced short-term relief, but the side effects began to be intolerable.

However, under treatment with CBD oil, the girl began to experience “a sustained decrease in anxiety and a constant improvement in the quality and quantity of sleep.”

LIMITATIONS IN THE STUDY OF THE CBD AND THE ANXIETY

However, this type of case reveals one of the many limitations that cannabinoid medical research still suffers, more a consequence of the legal status of cannabis than the competence of researchers. Most studies rely on personal or anecdotal reports, or very small population samples. In addition, there are practically no studies that determine the relationship between dose and effects.

While the necessary research continues to develop, we already know some of the mechanisms of interaction of CBD with our endocannabinoid system that allow us to establish its ability to reduce anxiety.

 

 

On one hand, CBD delays serotonin signaling, which boosts its antidepressant, anxiolytic, anti-addictive and antiemetic properties, as well as facilitating sleep. On the other hand, CBD is an allosteric modulator, which allows you to change the shape of GABA-A (Gamma-Aminobutyric), an inhibitory neurotransmitter, so that it improves the sedative effects of the receptor.

In conclusion, although science is still inconclusive, the accumulated evidence points in a clear direction: CBD has the ability to reduce anxiety. Of course, what we are trying to do now is to improve the quality of research with large long-term population studies, determining doses and routes of administration, to know the extent of CBD’s properties against anxiety.

ADDICTION AND OVERDOSE

Unlike cannabis, many pharmaceutical treatments result in physical addiction, including withdrawal or when abruptly interrupted. In addition, most of these medications can lead to an overdose, something that is impossible with marijuana (even with concentrates such as kief, hash oil and wax).

In 2014, a school teacher in California reported that she collapsed on the floor of her kitchen and was unconscious for more than an hour. Upon waking, he suffered tremors and hallucinations. “I felt these horrible shocks running through my head and my body; I couldn’t stop moving. Then I started to see things that weren’t there, creepy things. I didn’t know what was happening, but I worried that I was dying.

Unfortunately, these were simply the withdrawal symptoms of Xanax, a drug he used for more than eight years to combat insomnia, which his doctor believed was caused by anxiety.

THE STUDIES

In 1982, a study published in the journal Psychopharmacology revealed that CBD, the non-psychoactive cannabinoid that is commonly used to treat childhood epilepsy and put cancer in remission, decreased the anxiety experienced by large amounts of THC.

According to a 1999 study published in The Journal of Clinical Psychiatry, anxiety disorders cost the United States more than $ 40 billion, about a third of the nation’s $ 150 billion bills at the time.

In 2011, researchers from the University of Sao Paulo in Brazil gave doses of 400 mg of CBD to patients suffering from generalized social anxiety disorder (SAD), a condition that affects approximately 12 percent of Americans at some time of their lives. It was found that cerebral blood flow after CBD treatment indicates an anxiolytic (anti-anxiety) effect in the regions of the brain that control emotions.

He studies concluded: “In relation to placebo, CBD was associated with a significant decrease in subjective anxiety …. These results suggest that CBD reduces anxiety in SAD [Social Anxiety Disorder].” A study published in 2012 concluded that cannabis helps patients erase bad memories. The study observed: “For both anxiety and fear memory processing, endocannabinoid signaling can guarantee an adequate reaction to stressful events. Therefore, the ECS [endocannabinoid system] can be considered as a regulatory system for buffer damping. emotional responses. ”

Original source: http://nekwo.com/cbd-contra-la-ansiedad/

CBD AND CHRONIC PAIN

Every day there is more research in which it is shown that cannabis can be both an adjunct to existing conventional drugs to treat pain, as an alternative, natural, organic or ecological, effective and cheaper medicine for these drugs.

Pain is a universal disorder that is one of the biggest challenges for public health, both in clinical and economic terms and that not only affects the person who suffers it, but has an immense impact on their environment. There is nothing more desperate for a patient and his relatives than the first’s suffering of chronic pain, which when not treated properly can affect the dignity of the person. Numerous medical pathologies present with pain: arthritis, migraines, neuronal lesions, cancer and much more. Numerous drugs for the treatment of pain are currently available with a varying degree of efficacy, according to each patient and each pathology. Every day there is more research in which it is shown that cannabis can be both an adjunct to existing conventional drugs to treat pain, as a substitute medicine for these drugs. In fact, among all patients who use medicinal cannabis, one of the main pathologies for which they use it is to treat chronic pain.

Patients registered in the medical cannabis programs of the United States, 92.2% of patients use it for the treatment of severe and chronic pain (173). A sample of 628 medical cannabis users in Canada, pain was among the three main symptoms. 72% of the patients reported that cannabis was always useful and 24% that it was frequently. Although slightly more than half of the total sample said to use other medications; Of these, almost 80% said that cannabis had fewer side effects than other drugs (174). Having this reference, it can be understood that even in this sense the acceptance of medical cannabis can be favorable for the scientific world, providing important value to patients and their obstacles to good health.

Clinical trials in chronic pain relief

In relation to an international sample that included patients from different European and North American countries, the main medical condition for which patients used medical marijuana was also chronic pain (29.2%) (175). In a survey conducted in the United Kingdom among patients who self-medicated with cannabis, 40% reported doing so for the treatment of pain and, in Spain, a survey conducted on 2250 patients on the use of medical cannabis to treat their medical conditions, Of which 5.8% responded, 44.6% said they used it to treat pain symptoms (176). Regarding the relief of symptoms, in a North American survey composed of 97% of patients with chronic pain, the degree of relief they experienced when using cannabis was asked: on a scale of 0 to 10 pain intensity, the decrease The average was 5 points (7.8 to 2.8) between before and after using cannabis, which implies an average relative decrease of 64%. Half of the respondents also reported experiencing relief from stress and anxiety secondary to the disease and almost half (45%) reported relief from insomnia. The majority of patients (71%) did not report experiencing adverse effects (177). These analyzes and also in other statistics we see the increase in use and positive applications, it is a fact that in many countries the legalization for its medical use is already being implemented and it will grow in high demand.

 

Receptors, endogenous cannabinoid system and effects

The endocannabinoid system works retrograde, that is, inhibiting the activation of signals in response to excessive neuronal activity. This inhibition of neuronal firing manifests itself in the pain pathways in the form of analgesia and reduced pain sensitivity. There is a great abundance of CB1 receptors both in the brain areas responsible for processing pain, and in the peripheral nerves that transmit painful sensations to the brain, as well as in the brain areas related to the effective assessment of pain (fronto-limbic areas). On the other hand, CB2 receptors play an important role in reducing inflammatory processes and, above all, in signaling pain and can be of particular relevance in chronic pain states. In addition, both anandamide and 2-AG have been shown to have analgesic properties in numerous animal model studies (178). The knowledge of the involvement of the endogenous cannabinoid system, together with the accumulation of evidence from animal research, indicates that pharmacological modulation by means of cannabinoids is an extremely interesting strategy for the treatment of refractory and chronic pain states.

 

 

So far, clinical trials have been carried out both with marijuana and with different natural and synthetic cannabinoids in which more than 1000 patients have participated, showing efficacy in different types of chronic pain, the majority of studies with patients with neuropathic pain ( 179) (a type of pain resulting from a lesion in the central and / or peripheral nervous system) that occurs in diseases of the nervous system such as multiple sclerosis, but also in other types of diseases such as diabetes. Both THC and its synthetic analogs (nabilone and dronabinol) and Sativex have been found useful in clinical trials conducted so far. For its part, the CBD, in addition to also possessing analgesic properties (180), its ability to reduce the adverse psychological effects of THC, as well as its potential as an anxiolytic, makes its combination with THC, or its presence in herbal cannabis, help with THC to facilitate its analgesic property.

FDA

Not only THC and CBD, the main phytocannabinoids of the cannabis plant, have analgesic properties. Other non-psychoactive phytocannabinoids such as tetrahydrocannabivarin (THCV), cannabigerol (CBG) and cannabichrome (CBG) are also throwing evidence. And what is more interesting: it seems that the terpenes present in the cannabis plant also interact with the phytocannabinoids to synergistically enhance the analgesic effect with them (181). Terpenes are molecules that provide smell and aroma to many food products and are designated by different regulatory agencies, including the FDA (Food and Drug Administration), as “generally recognized as safe.” This phenomenon makes the use of the cannabis plant, with its rich composition in different cannabinoids and terpenes, considered a more interesting strategy than the administration of isolated compounds (182), and that there is even evidence of studies in animal models that They point in that direction (183).

Conclusion

Finally, there are more and more clinical studies (184), research based on surveys (185) and anecdotal cases (186), which show how in patients with chronic pain in treatment with opiates, the use of marijuana allows them to reduce the amounts of opioids they drink. Something, on the other hand, that is in line with animal and pharmacological research, in which there are abundant studies in which it has been found that the combination of cannabinoids with opiates acts synergistically (187) so that lower doses are needed of opiates to achieve the analgesic effect, which considerably reduces the risk of overdose, which, unlike cannabis, in the case of opiates can be fatal. In fact, a recently published study has found that in the US states where the use of medical marijuana is legalized, the number of overdose deaths caused by analgesic drugs, mainly opiates, is 24.8% lower than in the other states (188).

 

 

Reference and support

173. Bowles DW. (2012). Persons registered for medical marijuana in the United States. J Palliat Med. 15(1):9-11.

174. Walsh Z, Callaway R, Belle-Isle L, Capler R, Kay R, Lucas P, Holtzman S. (2013). Cannabis for therapeutic purposes: patient characteristics, access, and reasons for use. Int J Drug Policy. 24(6):511-6

175. Hazekamp A, Ware MA, Muller-Vahl KR, Abrams D, Grotenhermen F. (2013). The medicinal use of cannabis and cannabinoids–an international cross-sectional survey on administration forms. J Psychoactive Drugs. 45(3):199-210.

176. Borras R, Modamio P, Lastra CF, Marino EL. (2011). Medicinal Use of Cannabis in Spain. Altern Ther Health Med. 17(5):52- 54.

177. Webb CW, Webb SM. (2014). Therapeutic benefits of cannabis: a patient survey. Hawaii J Med Public Health. 73(4):109- 11.

178. Woodhams SG, Sagar DR, Burston JJ, Chapman V. (2015). The role of the endocannabinoid system in pain. Handb Exp Pharmacol. 227:119-43.

179. Fine PG, Rosenfeld MJ (2013). The endocannabinoid system, cannabinoids, and pain. Rambam Maimónides Med J. 4(4):e0022.

180. Maione S, Piscitelli F, Gatta L, Vita D, De Petrocellis L, Palazzo E, de Novellis V, Di Marzo V. (2011). Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action. Br J Pharmacol. 162(3):584-96

181. See foot 7 y 8.

182. Gertsch J, Pertwee RG, Di Marzo V. (2010). Phytocannabinoids beyond the Cannabis plant – do they exist? Br J Pharmacol. 160(3):523-9.

183. Comelli F, Giagnoni G, Bettoni I, Colleoni M, Costa B. (2008). Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved. Phytother Res. 22(8):1017-24.

184. Abrams DI, Couey P, Shade SB, Kelly ME, Benowitz NL. (2001). Cannabinoid-opioid interaction in chronic pain. Clin Pharmacol Ther. 90(6):844-51.

185. Degenhardt L, Lintzeris N, Campbell G, Bruno R, Cohen M, Farrell M, Hall WD. (2015). Experience of adjunctive cannabis use for chronic noncancer pain: findings from the Pain and Opioids IN Treatment (POINT) study. Drug Alcohol Depend. 147:144-50.

186. Krawitz M. (2015). Veterans Health Administration Policy on Cannabis as an Adjunct to Pain Treatment with Opiates. AMA J Ethics. 17(6):558-61.

187. Cichewicz DL. (2994). Synergistic interactions between cannabinoid and opioid analgesics. Life Sci. 74:1317–1324.

188. Bachhuber MA, Saloner B, Cunningham CO, Barry CL. (2014). Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010. JAMA Intern Med. 174(10):1668-73.

CBD OIL AND EPILEPSY IN CHILDREN

CBD and children health hope

In recent years, the medical use of medical cannabis has begun to expand throughout the world due to the benefits it reports for the treatment of some pathologies. In this regard, a study conducted at the Hebrew University of Jerusalem found that one of its components prevents early neuronal death and extends the life of brain cells, thus preventing degenerative diseases such as epilepsy.

 

Children in hospital

CBD and its benefits

Other research published in the American Journal of Medicine revealed that its medicinal consumption can reduce blood glucose levels and prevent the onset of obesity and diabetes.

It has also been shown that some components of medicinal cannabis have analgesic and anti-inflammatory properties that are very effective in treating pain and various autoimmune diseases. In fact, some studies have revealed that it could also be very effective in fighting tumors.

Although the Food and Drug Administration of the United States has not recognized it as a medicine since to do so it would need to have several rigorous and generalized clinical trials, which so far have not been performed, the truth is that several scientific studies have demonstrated its effectiveness in the treatment of some pathologies. In fact, in several states of USA its medicinal consumption has been legalized and it has even begun to be used in children to relieve multiple ailments.

Medical Cannabis

CBD oil and epilepsy in children

A study published recently in the Proceedings of the National Academy of Sciences found that regular consumption of cannabidiol for medical purposes can reduce the frequency and intensity of seizures in children with severe epilepsy who do not respond to other treatments. To arrive at these results, the researchers administered 137 patients cannabidiol orally for 3 months, in that period 6%, that is 12 participants, had to leave the treatment due to the side effects of the drug. However, in the rest of the patients, the seizures were reduced by approximately 54%.

 

Can all children benefit from cannabis treatment?

The American Pediatric Association recommends that medical cannabis treatment be limited exclusively to children who have limiting or life-threatening diseases, for which there is no other successful therapy. In the United States, many children have begun to benefit from its effects, but in Spain, the prescription of Cannabis treatment is still subject to strict control since it is only used to treat multiple sclerosis.
Hence, at least 300 families are “illegally” medicating their children with cannabidiol to relieve their various symptoms.

Seizures are much more dangerous than cannabis

if we have a child who is convulsing 300 times a day, who with each seizure loses an incredible amount of neurons, which has neurological damage, logically that the potential risk that perhaps in the future this early use may eventually generate five points less than CI is an argument that is not valid.

 

How Does CBD Affect Minors Suffering from Epilepsy?

Since 2008, the number of publications related to the extraction of cannabinoids, CBD oil, has increased considerably, with today more than 1205 publications in scientific bases such as PubMed. Among the research with human patients, examples such as Porter and Jacobson are worth mentioning. In this study, the evolution over time after doses of CBD oil is documented in a group of 19 children (ages 2 to 16), resistant to conventional antiepileptic treatments, it is also documented that these individuals were treated with about 12 different types of drugs, prior to the start of the study.

It was found that more than 50% of the individuals presented drastic reductions in the number of seizures after the dose of CBD oil and without the presence of typical adverse effects mentioned above. Even more interesting, the dosage provided was a daily dose of 0.5mg / kg up to 28.6 mg / kg.

During progressive follow-up, parents and family members report that patients were released from seizures after 4 months of uninterrupted daily use. Other cases mention up to 80% reduction in the frequency of attacks.

It should be noted that these improvements also influenced other aspects of patients’ daily lives such as: improved mood, better sleep and increased alertness.

Parallel studies in healthy patients, report having implemented doses as high as 600mg in the use of CBD oil, this dosage showed to be very well tolerated and without producing psychotic symptoms in individuals.

 

Happy childre cbd

Conclusion

The cannabis plant is made up of two main players: CBD and THC. “CBD is the non-psychoactive portion of the plant, so what that means is you won’t have any effects like euphoria,” says Junella Chin, DO, an osteopathic physician and medical cannabis experts. “You won’t feel sedated or altered in any way.”

Regarding this very important point, medical cannabis can be used for many different treatments, inclusive children can be relived from seizures.

In spite of the obstacles, the increasing investigations in this respect and the success stories reported by parents and users make the regulations change.

No parent wants to see their children suffer, and if cannabis can help children with chronic illnesses or cancer patients have a better quality of life, parental pressure will continue on legal bodies. Science is on your side.

Runing childre cbd

“The study was sponsored by the Alaska Mental Health Authority, the Arizona Department of Health Services, the California Department of Public Health, the Centers for Disease Control and Prevention (CDC), the CDC Foundation, the FDA, Mat-Su Health Foundation, Traffic Safety Administration, National Institutes of Health: National Cancer Institute and National Institutes of Health National Institute of Drug Abuse; the Oregon Health Authority, the Robert W. Woodruff Foundation, the Colorado Health Foundation, the Truth Initiative and the Washington State Department of Health. The National Academies of Science, Engineering and Medicine are private nonprofit institutions that provide independent and objective analysis and advice to the nation to solve complex problems and inform public policy decisions related to science, technology and medicine. The National Academies operate under a constitutional letter of 1863 to the National Academy of Sciences, signed by President Lincoln.”

 

CBD PSORIASIS AND-ECZEMA, IMMUNE SYSTEM.

Wellcome to a new and important article, but please let me tell you a bit about my self

I am a first son, father, husband, with a medical degree based in Phycho-bio-social- preparation profile, where we look into the patient and make a general study of how and where the patient lives, study and work.

DISCLAIMER

I am not trying to medicate anybody but share the knowledge I have gathered by curing my self for a better and longer life, as I see the CBD products are changing lives worldwide.

​I’m not taking any claim to diagnose or cure any disease with CBD oil, is really important to take and understand this point.

​And there is something to look at when we define it is:

Psoriasis and a ….

Psoriasis is a common, chronic, genetic, systemic inflammatory disease that is characterized by symptoms and signs such as elevated itchy plaques of raised red skin covered with thick silvery scales. Psoriasis is usually found on the elbows, knees, and scalp but can often affect the legs, trunk, and nails.

​This is a very exciting subject it is a big topic

​I want to talk about the benefits of CBD OIL for psoriasis and eczema in this article.

​Eczema used to be treated differently because we thought it was an allergy but now after around 5-6 years ago the science found out it is also an autoimmune condition.

The difference:

Psoriasis autoimmune condition causes the proliferation of skin cells, they stack on top of each other, not only does stack and creates scales a lot of inflammation and a real problem.

Eczema is more just inflammation and the itchy but.

When you heard about skin in conventional medicine what will do to resolve this is only a topical solution, and there is the problem, Eczema and Psoriasis is not really a skin problem, that it’s an inside problem expressing itself at the skin level. Literally an internal problem expressing itself on the surface of the skin.

The bigger problem becomes when the conventional pharmaceutics solution are telling you to use medication than suppress your immune system, because that is what is happening to cure your skin problem, does that sound right to you? I was told at school than my immune system is very important regarding my good health, so why I want to suppress that?

How CBD oil helps people?

There is a full treatment possible to accomplish with the CBD oil, how can we do this?

Topically: (CBD cream) Put it on your skin directly on your wounds for eczema and psoriasis, the antiinflammatory properties of CBD will help to calm it down, you can put on directly the CBD oil drop mix with a hemp organic oil on the affected areas also.

Internally: Put in directly CBD oil drops underneath your tongue, it will help to balance you internal inflammatory activity’s in your guts, and that is one of the many golden solutions than CBD does to you, calm, balance, anti-inflammatory job from the deep inside if where all the good bacteria and the immune system response directly when homeostasis is affected.

After looking at 2 different ways to make a more effective treatment, it takes 2 actions to have and achieve good results.

80% of the immune system lives in our gut’s, but also almost all autoimmune conditions have their origins somewhere from the guts as well, so when there is inflammation in the gut, the immune system triggers the fire in the whole immune system, and now the immune system is hyperactive and starts attacking skin cells and that’s how it flares psoriasis and eczema. So CBD oil calms down gut inflammation, and so the chain reaction of the system, which will stop the symptom of itchy, scratchy and relieving you from pain and psychologic misery.

CBD oil makes the gut to become stronger and may help reduce the leaky gut, all that has to be inside the gut will keep remaining inside and will not go in to the blood system and you immune system will be more relax and calm, and if there is already a leaky gut will heal the gut from leaking.

CBD oil has a very positive impact on the microbiota environment.

It is another alternative way of gets natural solutions for this health problem,

As is known and accepted very well today, one of the main functions of CBD is to attach to endogenous cannabinoid receptors in our organisms. After this union, a metabolic cascade of effects is produced, among which there is an anti-inflammatory tissue activity. Thanks to the fact that CBD is a molecule easily absorbed through the skin, and even more so through sublingual application (CBD oils), this molecule has proven to be a potential ally against the typical symptoms of this disease. Among other advantages of using CBD oil is that it does not present any type of toxicity or signs of overdose. Finally, this cannabinoid has antioxidant properties and some protection against UV rays, making the range of benefits of CBD ideal for patients with skin conditions.

Conclusion.

Within the cannabinoid research groups, there is a group led by Dr. Mechoulam in Israel, whose government has implemented a National Plan for Medicinal Cannabis a couple of months ago. This ambitious initiative has led not only researchers and doctors, but also the general public, to take a greater interest in these compounds and the great inherent therapeutic potential.

As it is present today, the potential of CBD oil can help in skin conditions such as psoriasis and the reduction of scales/rushes/itching /irritation.

The best products are from organic cultivations, the best way to support the CDB movement is to respect the fact of not THC.

 

art. The economist

“The doctor was blunt with Hannah Deacon, the mother of an epileptic boy. He told her that she would “never” get a prescription on the National Health Service (nhs) for medicine based on tetrahydrocannabinol (thc), the psychoactive ingredient in cannabis. The British government, too, was unhelpful, maintaining in February 2018 that cannabis had no medical value—a position that it had held for over 50 years, even as the country grew and exported cannabis for medicinal use. Yet within months, it had made a u-turn, accepting that Cannabis sativa had medical uses. Eight months after Ms Deacon made her first public plea for it, her son, Alfie, got thc-based medicine on the nhs.

Legislatures across the planet have been having similar changes of heart. This may presage broader legalisation. History suggests that when medical cannabis is permitted this is often the prelude to broader recreational access.”

(NHS)The National Health Service of the United Kingdom

The secret to the success of this therapy must be from the inside out.

ABOUT THIS PROJECT

I am a first son, father, husband, with a medical degree based in Physcho-bio-social- preparation profile, where we look into the patient and make a general study of how and where the patient lives, study and work. I am not trying to medicate anybody but share the knowledge I have gathered by curing my self for a better and longer life, as I see the CBD products are changing lives worldwide.

 

CBD IN MY LIFE

After some time I left the allopathy medicine world, and concentrated in holistic medicine and nutrition. I was aware of Cannabidiol, now total fascinated about the results taking place in my self, and taking away a serious pain I have in my lower backbone with CBD oil. I left my current job and move to a different country and culture with my wife and newborn.

 

OUR GOAL

I have created this project and web site with the intention of sharing my passion  with CBD, showing my self-experiments, and inspire people how has need for a better health, I’m sure than all this effort will provide ideas, steps, inspirations to let you know than there is always a new possibility, creative, different, fun, natural and more friendly to our goals in this journey call life.

I welcome you, and deeply thank you for bean here, let’s take this to another level and go for a better lifestyle once for all.

All the best.

CBDRSOUKI.